Background: Acute myeloid leukemia (AML) is a type of blood cancer characterized by
excessive growth of immature myeloid cells. Unfortunately, the prognosis of pediatric AML …

Abstract MicroRNA (miR)-381-3p is the newly discovered tumor-associated miRNA, which is
frequently associated with diverse human malignancies; but, it is still unknown about its …

MiRNAs play important roles in the development of both hematopoiesis and
leukemogenesis. The analysis of differential microRNA expression profiles may be a …

The study was aimed to explore the underlying mechanisms and identify the potential target
genes and key miRNAs for acute myeloid leukemia (AML) treatment by bioinformatics …

Correspondence e90© 2019 British Society for Haematology and John Wiley & Sons Ltd
British Journal of Haematology, 2020, 188, e80–e112 identification of differentially …

Simple Summary Survival rates for children with acute myeloid leukemia have significantly
improved in recent decades. Still, 20–30% will succumb to therapy-related toxicity and …

Abstract microRNA‑34a (miRNA‑34a) plays an important role in the pathogenesis of
leukemia. This study aimed to explore its role in the proliferation of HL‑60 cells and the …

Acute lymphoblastic leukemia (ALL) is a common malignancy in children. In this study, we
aimed to explore putative mechanisms of microRNA-155-5p (miR-155-5p) involvement in …

MicroRNAs (miRNAs) expression profiles were screened in plasma samples from pediatric
patients with acute lymphoblastic leukemia (ALL) and healthy controls, using qRT‐PCR …

Acute myeloid leukemia (AML) in children refers to a malignant tumor caused by the
abnormal proliferation of immature myeloid cells in the bone marrow and peripheral blood …