Brain repair: cell therapy in stroke

D Kalladka, KW Muir - Stem Cells and Cloning: Advances and …, 2014 - Taylor & Francis
Stroke affects one in every six people worldwide, and is the leading cause of adult disability.
Some spontaneous recovery is usual but of limited extent, and the mechanisms of late …

Stem cells in stroke repair: current success & future prospects

R Gopurappilly, R Pal… - CNS & Neurological …, 2011 - ingentaconnect.com
Stroke causes a devastating insult to the brain resulting in severe neurological deficits
because of a massive loss of different neurons and glia. In the United States, stroke is the …

Stem cells and stroke: opportunities, challenges and strategies

TC Burns, GK Steinberg - Expert opinion on biological therapy, 2011 - Taylor & Francis
Introduction: Stroke remains the leading cause of disability in the Western world. Despite
decades of work, no clinically effective therapies exist to facilitate recovery from stroke. Stem …

Cell-based therapies and functional outcome in experimental stroke

A Hicks, T Schallert, J Jolkkonen - Cell Stem Cell, 2009 - cell.com
One of the most promising frontiers in neuroscience is the potential for stem cells to treat
brain damage. Cell-based strategies are of particular interest in neurological conditions …

Cell-based therapy for ischemic stroke

J Zhang, M Chopp - Expert Opinion on Biological Therapy, 2013 - Taylor & Francis
Introduction: Stroke is a major cause of mortality and disability in adults worldwide.
Unfortunately, current therapy which targets vessel recanalization has a narrow treatment …

An update on translating stem cell therapy for stroke from bench to bedside

T Dailey, C Metcalf, YI Mosley, R Sullivan… - Journal of clinical …, 2013 - mdpi.com
With a constellation of stem cell sources available, researchers hope to utilize their potential
for cellular repair as a therapeutic target for disease. However, many lab-to-clinic …

Stem cell research in stroke: how far from the clinic?

O Lindvall, Z Kokaia - Stroke, 2011 - Am Heart Assoc
Stem cell-based approaches hold much promise as potential novel treatments to restore
function after stroke. Studies in animal models have shown that stem cell transplantation can …

Potential of stem/progenitor cells in treating stroke: the missing steps in translating cell therapy from laboratory to clinic

CV Borlongan, M Chopp, GK Steinberg… - Regenerative …, 2008 - Taylor & Francis
Accumulating laboratory evidence demonstrates the potential of transplanting
stem/progenitor cells for treating CNS disorders. The realization of neuroprotection or …

Cell based therapies for ischemic stroke: from basic science to bedside

X Liu, R Ye, T Yan, SP Yu, L Wei, G Xu, X Fan… - Progress in …, 2014 - Elsevier
Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …

Stem cell therapy in stroke

F Locatelli, A Bersano, E Ballabio… - Cellular and Molecular …, 2009 - Springer
Recent work has focused on cell transplantation as a therapeutic option following ischemic
stroke, based on animal studies showing that cells transplanted to the brain not only survive …