Macrophages as targets for drug delivery

S Gordon, S Rabinowitz - Advanced Drug Delivery Reviews, 1989 - Elsevier
Macrophages are widely distributed in many tissues of the body including lympho-
haemotopoietic organs, skin, gut, other portals of entry and the nervous system. They are …

Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases

W He, N Kapate, CW Shields IV, S Mitragotri - Advanced drug delivery …, 2020 - Elsevier
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Targeted drug delivery to macrophages

NK Jain, V Mishra, NK Mehra - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …

[HTML][HTML] Macrophage based drug delivery: Key challenges and strategies

Q Guo, ZM Qian - Bioactive Materials, 2024 - Elsevier
As a natural immune cell and antigen presenting cell, macrophages have been studied and
engineered to treat human diseases. Macrophages are well-suited for use as drug carriers …

Drug delivery to macrophages: challenges and opportunities

Y Pei, Y Yeo - Journal of Controlled Release, 2016 - Elsevier
Macrophages are prevalent in the body and have roles in almost every aspect of human
biology. They have often been considered a subject to avoid during drug delivery. However …

An overview on macrophage targeting: a promising approach

VD Vemuri, R Kushwaha, G Gowri… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Macrophages are immuno cells with high flexibility among hematopoietic system.
Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis …

Recent advances in macrophage-mediated drug delivery systems

T Liang, R Zhang, X Liu, Q Ding, S Wu… - International journal …, 2021 - Taylor & Francis
Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

[图书][B] The macrophage as therapeutic target

S Gordon - 2012 - books.google.com
During the past decade, the rapid growth of molecular and cellular knowledge of
macrophages, as a specialized host defense and homeostatic system, has begun to offer …

Macrophages in inflammation

N Fujiwara, K Kobayashi - Current Drug Targets-Inflammation & …, 2005 - ingentaconnect.com
The inflammatory process is usually tightly regulated, involving both signals that initiate and
maintain inflammation and signals that shut the process down. An imbalance between the …

Monocyte as an emerging tool for targeted drug delivery: a review

F Sabir, RK Farooq, N Ahmed - Current Pharmaceutical …, 2018 - ingentaconnect.com
Monocytes are leading component of the mononuclear phagocytic system that play a key
role in phagocytosis and removal of several kinds of microbes from the body. Monocytes are …