Transplanted adult spinal cord–derived neural stem/progenitor cells promote early functional recovery after rat spinal cord injury

AM Parr, I Kulbatski, T Zahir, X Wang, C Yue, A Keating… - Neuroscience, 2008 - Elsevier
We examined the effect of spinal cord–derived neural stem/progenitor cells (NSPCs) after
delayed transplantation into the injured adult rat spinal cord with or without earlier …

Fate of transplanted adult neural stem/progenitor cells and bone marrow–derived mesenchymal stromal cells in the injured adult rat spinal cord and impact on …

AM Parr, I Kulbatski, XH Wang, A Keating, CH Tator - Surgical neurology, 2008 - Elsevier
Background Neural stem/progenitor cells derived from the ependymal region of the spinal
cord may have the ability to regenerate the injured mammalian spinal cord as they do in …

Transplantation of human neural stem cells for spinal cord injury in primates

A Iwanami, S Kaneko, M Nakamura… - Journal of …, 2005 - Wiley Online Library
Recent studies have shown that delayed transplantation of neural stem/progenitor cells
(NSPCs) into the injured spinal cord can promote functional recovery in adult rats …

Neuroprotective effects of human spinal cord-derived neural precursor cells after transplantation to the injured spinal cord

M Emgård, J Piao, H Aineskog, J Liu… - Experimental …, 2014 - Elsevier
To validate human neural precursor cells (NPCs) as potential donor cells for transplantation
therapy after spinal cord injury (SCI), we investigated the effect of NPCs, transplanted as …

Stem cell-based cell therapy for spinal cord injury

BG Kim, DH Hwang, SI Lee, EJ Kim… - Cell …, 2007 - journals.sagepub.com
Traumatic injuries to the spinal cord lead to severe and permanent neurological deficits.
Although no effective therapeutic option is currently available, recent animal studies have …

Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord

DJ Webber, EJ Bradbury, SB McMahon… - Regenerative …, 2007 - Taylor & Francis
Endogenous repair after injury in the adult CNS is limited by a number of factors including
cellular loss, inflammation, cavitation and glial scarring. Spinal cord neural progenitor cells …

Human spinal oligodendrogenic neural progenitor cells promote functional recovery after spinal cord injury by axonal remyelination and tissue sparing

N Nagoshi, M Khazaei, JE Ahlfors… - Stem cells …, 2018 - academic.oup.com
Cell transplantation therapy utilizing neural precursor cells (NPCs) is a conceptually
attractive strategy for traumatic spinal cord injury (SCI) to replace lost cells, remyelinate …

[HTML][HTML] Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury

G Kumagai, Y Okada, J Yamane, N Nagoshi… - PloS one, 2009 - journals.plos.org
Transplantation of neural stem/progenitor cells (NS/PCs) following the sub-acute phase of
spinal cord injury (SCI) has been shown to promote functional recovery in rodent models …

[HTML][HTML] Human conditionally immortalized neural stem cells improve locomotor function after spinal cord injury in the rat

T Amemori, N Romanyuk, P Jendelova… - Stem cell research & …, 2013 - Springer
Introduction A growing number of studies have highlighted the potential of stem cell and
more-differentiated neural cell transplantation as intriguing therapeutic approaches for …

BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury

M Sasaki, C Radtke, AM Tan, P Zhao… - Journal of …, 2009 - Soc Neuroscience
Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been
shown to improve functional outcome in spinal cord injury (SCI). We transplanted MSCs …