[HTML][HTML] AL amyloidosis: Unfolding a complex disease

R Lu, TA Richards - Journal of the advanced practitioner in …, 2019 - ncbi.nlm.nih.gov
Light chain (AL) amyloidosis is a rare plasma cell dyscrasia. An estimated 12,000 people
live with the disease in the United States. AL amyloidosis occurs from the misfolding of …

[HTML][HTML] AL amyloidosis: advances in diagnosis and management

Y Koh - Blood research, 2020 - synapse.koreamed.org
Light chain (AL) amyloidosis is a disease in which malignant plasma cell clones affect
multiple organs including the heart and kidney. The mechanism for organ function …

[HTML][HTML] Light chain (AL) amyloidosis: update on diagnosis and management

M Rosenzweig, H Landau - Journal of Hematology & Oncology, 2011 - Springer
Light chain (AL) amyloidosis is a plasma cell dyscrasia characterized by the pathologic
production of fibrillar proteins comprised of monoclonal light chains which deposit in tissues …

[HTML][HTML] Role of Palliative Care in the Supportive Management of AL Amyloidosis—A Review

MH Habib, YKR Tiger, D Dima, M Schlögl… - Journal of Clinical …, 2024 - mdpi.com
Light chain amyloidosis is a plasma–cell disorder with a poor prognosis. It is a progressive
condition, causing worsening pain, disability, and life-limiting complications involving …

Multiorgan involvement by amyloid light chain amyloidosis

G Li, D Han, S Wei, H Wang… - Journal of International …, 2019 - journals.sagepub.com
Amyloid light chain (AL) amyloidosis is a protein conformational disease. AL amyloidosis
results from aggregation of misfolded proteins that are deposited in tissues as amyloid fibrils …

Amyloidosis: pathogenesis and new therapeutic options

G Merlini, DC Seldin, MA Gertz - Journal of Clinical Oncology, 2011 - ascopubs.org
The systemic amyloidoses are a group of complex diseases caused by tissue deposition of
misfolded proteins that results in progressive organ damage. The most common type …

New and developing therapies for AL amyloidosis

G Zumbo, O Sadeghi-Alavijeh… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Systemic light-chain (AL) amyloidosis is an infiltrative disorder associated with
an underlying plasma cells dyscrasia, in which monoclonal immunoglobulin light chains …

Diagnosis and management of systemic light chain AL amyloidosis

D Bhutani, S Lentzsch - Pharmacology & Therapeutics, 2020 - Elsevier
AL amyloidosis is a plasma cell disorder leading to the production and extracellular
deposition of abnormal immunoglobulin light chains called amyloid. The pathogenesis of the …

New insights and modern treatment of AL amyloidosis

CP Chaulagain, RL Comenzo - Current hematologic malignancy reports, 2013 - Springer
Systemic amyloidosis is a rare disease that is rarely cured. Systemic immunoglobulin light-
chain amyloidosis (AL) is the most common type, usually the result of monoclonal light …

AL amyloidosis: untangling new therapies

S Bal, H Landau - Hematology, 2021 - ashpublications.org
Systemic light chain (AL) amyloidosis is a protein misfolding disorder characterized by the
deposition of abnormal immunoglobulin light chains in fibrillary aggregates, resulting in end …