Quinoline and quinolone dimers and their biological activities: An overview
XM Chu, C Wang, W Liu, LL Liang, KK Gong… - European journal of …, 2019 - Elsevier
Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …
Recent update on antibacterial and antifungal activity of quinoline scaffolds
A Dorababu - Archiv der Pharmazie, 2021 - Wiley Online Library
Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
Recent insight into the biological activities and SAR of quinolone derivatives as multifunctional scaffold
Quinolones are a type of bicyclic privileged building block with immense therapeutic
potential. They are known for their crucial role in modulating numerous diseases conditions …
potential. They are known for their crucial role in modulating numerous diseases conditions …
Quinolone hybrids and their anti-cancer activities: An overview
F Gao, X Zhang, T Wang, J Xiao - European journal of medicinal chemistry, 2019 - Elsevier
The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …
Recent advances in the synthetic and medicinal perspective of quinolones: A review
In the modern scenario, the quinolone scaffold has emerged as a very potent motif
considering its clinical significance. Quinolones possess wide range of pharmacological …
considering its clinical significance. Quinolones possess wide range of pharmacological …
Quinolines and structurally related heterocycles as antimalarials
The quinoline scaffold is prevalent in a variety of pharmacologically active synthetic and
natural compounds. The discovery of chloroquine, the most famous drug containing this …
natural compounds. The discovery of chloroquine, the most famous drug containing this …
Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
[HTML][HTML] Quinolone: a versatile therapeutic compound class
The discovery of nalidixic acid is one pinnacle in medicinal chemistry, which opened a new
area of research that has led to the discovery of several life-saving antimicrobial agents …
area of research that has led to the discovery of several life-saving antimicrobial agents …
The 4-quinolone-3-carboxylic acid motif as a multivalent scaffold in medicinal chemistry
C Mugnaini, S Pasquini, F Corelli - Current medicinal chemistry, 2009 - ingentaconnect.com
Quinolones are among the most common frameworks present in the bioactive molecules
and hence represent an attractive starting point for the design of combinatorial libraries …
and hence represent an attractive starting point for the design of combinatorial libraries …
Quinine conjugates and quinine analogues as potential antimalarial agents
RA Jones, SS Panda, CD Hall - European journal of medicinal chemistry, 2015 - Elsevier
Malaria is a tropical disease, prevalent in Southeast Asia and Africa, resulting in over half a
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …