Aims The purpose of this study is to evaluate an aggregate influence of prostate cancer
(PCa) susceptibility variants on the development of PCa in Korean men by using the …

BACKGROUND Genome‐wide association studies (GWAS) have identified more than 30
single nucleotide polymorphisms (SNPs) that were reproducibly associated with prostate …

Purpose To develop and evaluate the performance of a polygenic risk score (PRS)
constructed in a Korean male population to predict clinically significant prostate cancer …

Decreasing costs of genetic testing and interest in disease inheritance has changed the
landscape of cancer prediction in prostate cancer (PCa), and guidelines now include …

Objectives Genome-wide association studies have revealed over 200 genetic susceptibility
loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be …

Prostate cancer (PCa) is one of the most common cancers among men in Western
developed countries and its incidence has increased considerably in many other parts of the …

Background Genome‐wide association studies have identified over 100 single‐nucleotide
polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores …

Genome-wide association studies (GWAS) have identified~ 170 genetic loci associated with
prostate cancer (PCa) risk, but most of them were identified in European populations. We …

Background Polygenic risk score (PRS) has shown promise in predicting prostate cancer
(PCa) risk. However, the application of PRS in non‐European ancestry was poorly studied …

Emerging data from several studies regarding PRS in PCa could be the solution to adding
predictive value to PCa risk estimation. Although commercial markers are available …