Vascular endothelial (VE)-cadherin, endothelial adherens junctions, and vascular disease

MG Lampugnani, E Dejana… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Endothelial cell–cell adherens junctions (AJs) supervise fundamental vascular functions,
such as the control of permeability and transmigration of circulating leukocytes, and the …

VE-cadherin at a glance

L Bravi, E Dejana, MG Lampugnani - Cell and tissue research, 2014 - Springer
Although being a monolayer the vascular endothelium controls fundamental vessel
functions such as permeability, leukocyte extravasation and angiogenesis. The endothelial …

VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity

M Giannotta, M Trani, E Dejana - Developmental cell, 2013 - cell.com
VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …

The control of endothelial cell functions by adherens junctions

MG Lampugnani, E Dejana - Vascular Development: Novartis …, 2007 - Wiley Online Library
Cell to cell junctions are important regulators of endothelial responses both in quiescent and
angiogenic vessels. Endothelial cells express tight and adherens junctional structures …

VE-cadherin: at the front, center, and sides of endothelial cell organization and function

ES Harris, WJ Nelson - Current opinion in cell biology, 2010 - Elsevier
Endothelial cells form cell–cell adhesive structures, called adherens and tight junctions,
which maintain tissue integrity, but must be dynamic for leukocyte transmigration during the …

The role of adherens junctions and VE-cadherin in the control of vascular permeability

E Dejana, F Orsenigo… - Journal of cell …, 2008 - journals.biologists.com
Endothelial cells control the passage of plasma constituents and circulating cells from blood
to the underlying tissues. This specialized function is lost or impaired in several pathological …

Vascular endothelial (VE)-cadherin: only an intercellular glue?

E Dejana, G Bazzoni, MG Lampugnani - Experimental cell research, 1999 - Elsevier
Data collected during the past years indicate that AJ-and more specifically VE-cadherin play
an important role in endothelial cell biology. VE-cadherin may transfer information …

Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin

D Gulino, E Delachanal, E Concord, Y Genoux… - Journal of Biological …, 1998 - ASBMB
Although cadherins appear to be necessary for proper cell-cell contacts, the physiological
role of VE-cadherin (vascular endothelium cadherin) in adult tissue has not been clearly …

Adherens junctions in endothelial cells regulate vessel maintenance and angiogenesis

MG Lampugnani, E Dejana - Thrombosis research, 2007 - Elsevier
Cell to cell junctions direct endothelial responses both in quiescent and angiogenic vessels.
Endothelial cells express both tight and adherens junctions. Although different in their …

Molecular mechanism of VE-cadherin in regulating endothelial cell behaviour during angiogenesis

W Nan, Y He, S Wang, Y Zhang - Frontiers in Physiology, 2023 - frontiersin.org
Vascular endothelial (VE)-cadherin, an endothelium-specific adhesion protein, is found in
the junctions between endothelial cells (ECs). It's crucial to maintain the homogeneity of …