Macrophage biology in development, homeostasis and disease
TA Wynn, A Chawla, JW Pollard - Nature, 2013 - nature.com
Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …
and show great functional diversity. They have roles in development, homeostasis, tissue …
New insights into the multidimensional concept of macrophage ontogeny, activation and function
Macrophages have protective roles in immunity to pathogens, tissue development,
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …
Tissue biology perspective on macrophages
Y Okabe, R Medzhitov - Nature immunology, 2016 - nature.com
Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …
Physiology and diseases of tissue-resident macrophages
Embryo-derived tissue-resident macrophages are the first representatives of the
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration
JA Stefater, S Ren, RA Lang, JS Duffield - Trends in molecular medicine, 2011 - cell.com
Over the past decade, modern genetic tools have permitted scientists to study the function of
myeloid lineage cells, including macrophages, as never before. Macrophages were first …
myeloid lineage cells, including macrophages, as never before. Macrophages were first …
[HTML][HTML] Tissue-specific macrophages: how they develop and choreograph tissue biology
Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
[HTML][HTML] Tissue macrophages: heterogeneity and functions
S Gordon, A Plüddemann - BMC biology, 2017 - Springer
Macrophages are present in all vertebrate tissues, from mid-gestation throughout life,
constituting a widely dispersed organ system. They promote homeostasis by responding to …
constituting a widely dispersed organ system. They promote homeostasis by responding to …
Monocytes and macrophages: developmental pathways and tissue homeostasis
Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …
The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis
Macrophages provide a critical systemic network cells of the innate immune system.
Emerging data suggest that in addition, they have important tissue-specific functions that …
Emerging data suggest that in addition, they have important tissue-specific functions that …