The endocannabinoid system has been suspected to contribute to the association of visceral
fat accumulation with metabolic diseases. We determined whether circulating …

Obesity is the main risk factor for the development of type 2 diabetes. Activation of the central
endocannabinoid system increases food intake and promotes weight gain. Blockade of the …

Background The endocannabinoids, anandamide and 2-AG, are produced by adipocytes,
where they stimulate lipogenesis via cannabinoid CB 1 receptors and are under the …

Objective: The link between excess intra-abdominal adiposity (IAA) and metabolic
complications leading to type 2 diabetes and cardiovascular disease is well recognized …

Objective: Recently, an activation of the endocannabinoid system during obesity has been
reported. More particularly, it has been demonstrated that hypothalamic levels of both …

Background: The endogenous cannabinoid system participates in the regulation of energy
balance, and its dysregulation may be implicated in the pathogenesis of obesity. Adipose …

The endocannabinoid system (ECS) controls energy balance by regulating both energy
intake and energy expenditure. Endocannabinoid levels are elevated in obesity suggesting …

Aims/hypothesis We previously reported that the plasma levels of the endocannabinoid, 2-
arachidonoylglycerol (2-AG), in a cohort of viscerally obese men are directly correlated with …

An activation of the endocannabinoid system (ECS) in obesity with increased concentrations
of endocannabinoids in several tissues and in the circulation is described in this review. This …

The endocannabinoid system is involved in a wide range of processes including the control
of energy acquisition and expenditure. Endocannabinoids and their receptors are present in …