In epithelial tissues, cells constantly generate and transmit forces between each other.
Forces generated by the actomyosin cytoskeleton regulate tissue shape and structure and …

Cell shape changes underlie a large set of biological processes ranging from cell division to
cell motility. Stereotyped patterns of cell shape changes also determine tissue remodeling …

During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …

Tissue size, shape, and organization reflect individual cell behaviors such as proliferation,
shape change, and movement. Evidence suggests that mechanical signals operate in …

Cells integrate biochemical and mechanical information to function within multicellular
tissue. Within developing and remodeling tissues, mechanical forces contain instructive …

Mechanical forces are now recognized as key cellular effectors that together with genetic
and cellular signals physically shape and pattern tissues and organs during development …

Cortical forces drive a variety of cell shape changes and cell movements during tissue
morphogenesis. While the molecular components underlying these forces have been largely …

The propagation of force in epithelial tissues requires that the contractile cytoskeletal
machinery be stably connected between cells through E-cadherin-containing adherens …

▪ Abstract Mechanical forces play an important role in the organization, growth, maturation,
and function of living tissues. At the cellular level, many of the biological responses to …

A universal principle of all living cells is the ability to sense and respond to mechanical
stimuli which is essential for many biological processes. Recent efforts have identified …