SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function
Y Du, G Hou, H Zhang, J Dou, J He, Y Guo… - Nucleic acids …, 2018 - academic.oup.com
Abstract The methyltransferase like 3 (METTL3) is a key component of the large N6-
adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine …
adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine …
Human METTL16 is a N6‐methyladenosine (m6A) methyltransferase that targets pre‐mRNAs and various non‐coding RNAs
AS Warda, J Kretschmer, P Hackert, C Lenz… - EMBO …, 2017 - embopress.org
Abstract N 6‐methyladenosine (m6A) is a highly dynamic RNA modification that has recently
emerged as a key regulator of gene expression. While many m6A modifications are installed …
emerged as a key regulator of gene expression. While many m6A modifications are installed …
METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing
YT Goh, CWQ Koh, DY Sim, X Roca… - Nucleic Acids …, 2020 - academic.oup.com
Abstract N 6-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells
to generate N 6, 2′-O-dimethyladenosine (m6Am). Identification of the methyltransferase …
to generate N 6, 2′-O-dimethyladenosine (m6Am). Identification of the methyltransferase …
Structural insights into the RNA methyltransferase domain of METTL16
A Ruszkowska, M Ruszkowski, Z Dauter, JA Brown - Scientific reports, 2018 - nature.com
Abstract N 6-methyladenosine (m6A) is an abundant modification in messenger RNA and
noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) …
noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) …
METTL16, methyltransferase-like protein 16: current insights into structure and function
A Ruszkowska - International Journal of Molecular Sciences, 2021 - mdpi.com
Methyltransferase-like protein 16 (METTL16) is a human RNA methyltransferase that installs
m6A marks on U6 small nuclear RNA (U6 snRNA) and S-adenosylmethionine (SAM) …
m6A marks on U6 small nuclear RNA (U6 snRNA) and S-adenosylmethionine (SAM) …
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Abstract N 6-methyladenosine (m6A) is the most prevalent and reversible internal
modification in mammalian messenger and noncoding RNAs. We report here that human …
modification in mammalian messenger and noncoding RNAs. We report here that human …
[HTML][HTML] The m6A methyltransferase METTL3 promotes translation in human cancer cells
METTL3 is an RNA methyltransferase implicated in mRNA biogenesis, decay, and
translation control through N 6-methyladenosine (m 6 A) modification. Here we find that …
translation control through N 6-methyladenosine (m 6 A) modification. Here we find that …
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
Dear Editor, Protein coding mRNAs and non-coding RNAs are extensively modified by
chemical modifications, 1 including methylation of the N6 position of adenosine (m6A). 2 …
chemical modifications, 1 including methylation of the N6 position of adenosine (m6A). 2 …
Characterization of METTL16 as a cytoplasmic RNA binding protein
DJ Nance, ER Satterwhite, B Bhaskar, S Misra… - PLoS …, 2020 - journals.plos.org
mRNA modification by N6-methyladenosine (m6A) is involved in many post-transcriptional
regulation processes including mRNA stability, splicing and promotion of translation …
regulation processes including mRNA stability, splicing and promotion of translation …
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
ZC Zeng, Q Pan, YM Sun, HJ Huang, XT Chen… - EMBO …, 2023 - embopress.org
Abstract N 6‐Methyladenosine (m6A) is an important RNA modification catalyzed by
methyltransferase‐like 3 (METTL3) and METTL14. m6A homeostasis mediated by the …
methyltransferase‐like 3 (METTL3) and METTL14. m6A homeostasis mediated by the …