Increased maternal-fetal transport of fat in diabetes assessed by polyunsaturated fatty acid content in fetal lipids

R Goldstein, E Levy, E Shafrir - Neonatology, 1985 - karger.com
The distribution of fatty acids was determined by gas-liquid chromatography in total lipid and
triglyceride fraction of extracts of several tissues of streptozotocin-diabetic rats and their …

Placental function in maternal-fetal fat transport in diabetes

E Shafrir, V Barash - Neonatology, 1987 - karger.com
High levels of triglycerides (TG) and free fatty acids (FFA) in maternal plasma, in diabetes,
promote fat passage to the fetus. In the streptozotocin-diabetic rat a significant correlation …

Maternal-fetal fat transport versus new fat synthesis in the pregnant diabetic rat

E Shafrir, S Khassis - Diabetologia, 1982 - Springer
Rats were made diabetic by the injection of streptozotocin on day 12 of pregnancy and were
investigated on days 17 and 20 of pregnancy. A significant correlation between both …

Placental transfer of non-esterified fatty acids in normal and diabetic pregnancy

CR Thomas - Neonatology, 1987 - karger.com
The placental transfer of non-esterified fatty acids, predominantly in the direction of mother to
fetus, is regulated on a gross scale by the transplacental non-esterified fatty acid gradient …

Lipid metabolism in the fetus and the newborn

E Herrera, E Amusquivar - Diabetes/metabolism research and …, 2000 - Wiley Online Library
During late gestation, although maternal adipose tissue lipolytic activity becomes enhanced,
lipolytic products cross the placenta with difficulty. Under fasting conditions, free fatty acids …

Differences in the implications of maternal lipids on fetal metabolism and growth between gestational diabetes mellitus and control pregnancies

UM Schaefer‐Graf, K Meitzner… - Diabetic …, 2011 - Wiley Online Library
Diabet. Med. 28, 1053–1059 (2011) Abstract Aims To evaluate the potential contribution of
maternal glucose and lipids to fetal metabolic variables and growth in pregnancies with …

Maternal and fetal lipid metabolism under normal and gestational diabetic conditions

E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …

Transferred maternal fatty acids stimulate fetal adipogenesis and lead to neonatal and adult obesity

AJ Szabo - Medical hypotheses, 2019 - Elsevier
The prevalence of adult and childhood obesity are increasing. Most of the human newborn's
body fat accumulates in the last half of intrauterine life. Fat in the fetus was thought to be …

Placental fatty acid transfer: a key factor in fetal growth

E Larqué, A Pagán, MT Prieto, JE Blanco… - Annals of Nutrition and …, 2014 - karger.com
The functionality of the placenta may affect neonatal adiposity and fetal levels of key
nutrients such as long-chain polyunsaturated fatty acids. Fetal macrosomia and its …

Implications of lipids in neonatal body weight and fat mass in gestational diabetic mothers and non-diabetic controls

E Herrera, H Ortega-Senovilla - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review Maternal lipid metabolism greatly changes during pregnancy
and we review in this article how they influence fetal adiposity and growth under non …