[HTML][HTML] Targeting the immune microenvironment in the treatment of head and neck squamous cell carcinoma

HC Wang, LP Chan, SF Cho - Frontiers in Oncology, 2019 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive solid tumor, with
a 5-year mortality rate of~ 50%. The development of immunotherapies has improved the …

Tumor immune microenvironment in head and neck cancers

SMY Chen, AL Krinsky, RA Woolaver… - Molecular …, 2020 - Wiley Online Library
Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …

[HTML][HTML] The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications

P Economopoulou, C Perisanidis… - Annals of …, 2016 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) carries a poor prognosis, with low
survival rates for advanced stage tumors and minimal improvement in survival trends …

Immunology and immunotherapy of head and neck cancer

RL Ferris - Journal of clinical oncology, 2015 - ascopubs.org
The immune system plays a key role in the development, establishment, and progression of
head and neck squamous cell carcinoma (HNSCC). A greater understanding of the …

[HTML][HTML] Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma

Y Qin, X Zheng, W Gao, B Wang, Y Wu - Molecular Therapy-Oncolytics, 2021 - cell.com
Head and neck squamous cell carcinomas (HNSCCs) are a type of common malignant
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …

Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment

AT Ruffin, H Li, L Vujanovic, DP Zandberg… - Nature Reviews …, 2023 - nature.com
Targeted immunotherapy has improved patient survival in head and neck squamous cell
carcinoma (HNSCC), but less than 20% of patients produce a durable response to these …

[HTML][HTML] Current status and perspective of tumor immunotherapy for head and neck squamous cell carcinoma

C Yu, Q Li, Y Zhang, ZF Wen, H Dong… - Frontiers in Cell and …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) have a high incidence and mortality
rate, and investigating the pathogenesis and potential therapeutic strategies of HNSCC is …

Immune alterations and immunotherapy prospects in head and neck cancer

V Varilla, J Atienza, CA Dasanu - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: Several literature sources have suggested that subjects with head and neck
squamous cell carcinoma (HNSCC) display significant abnormalities of immunocompetent …

[HTML][HTML] A review on the advances and challenges of immunotherapy for head and neck cancer

G Cheng, H Dong, C Yang, Y Liu, Y Wu, L Zhu… - Cancer Cell …, 2021 - Springer
Head and neck cancer (HNC), which includes lip and oral cavity, larynx, nasopharynx,
oropharynx, and hypopharynx malignancies, is one of the most common cancers worldwide …

Understanding the tumor microenvironment in head and neck squamous cell carcinoma

HS Rad, Y Shiravand, P Radfar… - Clinical & …, 2022 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) represents a heterogeneous group of
tumors. While significant progress has been made using multimodal treatment, the 5‐year …