The promise and perils of 'targeted therapy'of advanced ovarian cancer

M Markman - Oncology, 2008 - karger.com
For several reasons, ovarian cancer is an excellent malignancy to consider the use of
'targeted'therapeutic strategies. However, to date, despite considerable effort, there remains …

Promising molecular targets in ovarian cancer

S Blagden, H Gabra - Current opinion in oncology, 2009 - journals.lww.com
Using targeted agents in ovarian cancer, we are discovering not only how these novel
therapies work but are also unveiling the complex 'wiring'of the disease itself, and the …

New perspectives on targeted therapy in ovarian cancer

JIG Coward, K Middleton, F Murphy - International journal of …, 2015 - Taylor & Francis
Epithelial ovarian cancer remains the most lethal gynecologic malignancy. During the last
15 years, there has been only marginal improvement in 5 year overall survival. These …

Targeted agents in ovarian cancer

TS Kristedja, RJ Morgan, M Cristea - Women's Health, 2010 - journals.sagepub.com
Despite recent advances in the treatment of ovarian cancer, a large majority of women with
this diagnosis will die from recurrence of their disease. Targeted therapies, in the form of …

Targeted therapy for epithelial ovarian cancer

S Sharma, K Odunsi - Expert opinion on therapeutic targets, 2005 - Taylor & Francis
Ovarian cancer is the leading cause of death in women with gynecological malignancies
and overall survival for patients with advanced epithelial ovarian cancer (EOC) remains …

Beyond chemotherapy: targeted therapies in ovarian cancer

TA Yap, CP Carden, SB Kaye - Nature Reviews Cancer, 2009 - nature.com
Ovarian cancer is the leading cause of death from gynaecological malignancies in the
Western world. Despite the evolution of surgical techniques and meticulously designed …

New hopes and promises in the treatment of ovarian cancer focusing on targeted treatment—a narrative review

M Satora, K Kułak, B Zaremba, A Grunwald… - Frontiers in …, 2024 - frontiersin.org
Unfortunately, ovarian cancer is still diagnosed most often only in an advanced stage and is
also the most lethal gynecological cancer. Another problem is the fact that treated patients …

Targeted therapies in epithelial ovarian cancer

NI Barrena Medel, JD Wright, TJ Herzog - Journal of oncology, 2010 - Wiley Online Library
Epithelial ovarian cancer remains a major women′ s health problem due to its high
lethality. Despite great efforts to develop effective prevention and early detection strategies …

Targeted therapy for epithelial ovarian cancer: current status and future prospects

HT See, JJ Kavanagh, W Hu, RC Bast - International Journal of …, 2003 - ijgc.bmj.com
Despite advances in surgery and chemotherapy, less than 20% of patients with stage III or IV
ovarian cancer survive long-term. In the past, cytotoxic regimens have been developed …

Targeting the hallmarks of ovarian cancer: The big picture

M Petrillo, C Nero, G Amadio, D Gallo, A Fagotti… - Gynecologic …, 2016 - Elsevier
Objective As a result of relevant achievements in the field of translational research, several
active drugs and multiple biological targets are available in ovarian cancer (OC). In this …