Reviewing the current picture of uremic toxicity reveals its complexity. Focusing on
cardiovascular damage as a model of uremic effects resulting in substantial morbidity and …

In the last decade, uremic toxicity as a potential cause for the excess of cardiovascular
disease and mortality observed in chronic kidney disease gained more and more interest …

Patients with end-stage kidney disease (ESKD) on maintenance hemodialysis are subject to
a high burden of inflammation and cardiovascular disease, driven at least in part by …

New insights in uremic toxins. The retention in the body of compounds, which normally are
secreted into the urine results in a clinical picture, called the uremic syndrome. The retention …

The kidneys and heart share functions with the common goal of maintaining homeostasis.
When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or …

Chronic kidney disease (CKD) is a condition that affects approximately 10% of the adult
population in developed countries. In patients with CKD adequate renal clearance is …

The uremic syndrome is characterized by an accumulation of uremic toxins due to
inadequate kidney function. The European Uremic Toxin (EUTox) Work Group has listed 90 …

Advances in our understanding of uremic retention solutes, and improvements in
hemodialysis membranes and other techniques designed to remove uremic retention …

Background: Retention of uremic toxins in patients with chronic kidney disease (CKD)
negatively affects multiple organ systems, including the cardiovascular system, resulting in …

Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …