Polyglutamine (polyQ)-expansions in differentproteins cause nine neurodegenerative
diseases. While polyQ aggregation is a key pathological hallmark of these diseases, how …

Polyglutamine (polyQ) expansion causes nine inherited neurodegenerative disorders,
including Huntington's Disease, Spinobulbar Muscular Atrophy, Dentatorubral …

The polyglutamine (polyQ) diseases consist of nine neurodegenerative diseases in which a
polyQ tract expansion leads to protein misfolding and subsequent aggregation. Even when …

Polyglutamine (polyQ) repeat-containing proteins are widespread in the human proteome
but only nine of them are associated with highly incapacitating neurodegenerative disorders …

Over 100 human cellular proteins contain a repetitive polyglutamine tract, however, only
nine of these proteins are associated with disease. In these proteins, the expanded polyQ …

Protein aggregation is a key mechanism involved in neurodegeneration associated with
Alzheimer's, Parkinson's and Huntington's diseases. Nine diseases (including Huntington's) …

The polyglutamine (polyQ) diseases are a class of inherited neurodegenerative diseases
including Huntington's disease, caused by the expansion of a polyQ stretch within each …

In nine members of polyglutamine (polyQ) diseases, CAG repeat expansions of their
responsible genes are observed. The disease is considered to be caused by the formation …

Polyglutamine (polyQ) disorders, including Huntington's disease (HD), are caused by
expansion of polyQ-encoding repeats within otherwise unrelated gene products. In polyQ …

The presence and aggregation of misfolded proteins has deleterious effects in the nervous
system. Among the various diseases caused by misfolded proteins is the family of the …