[HTML][HTML] Structure, function, and genetics of lipoprotein (a)

K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

Lipoprotein (a): resurrected by genetics

F Kronenberg, G Utermann - Journal of internal medicine, 2013 - Wiley Online Library
Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

Lipoprotein (a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop …

S Tsimikas, JL Hall - Journal of the American College of Cardiology, 2012 - jacc.org
Recent published studies have provided increasing evidence that lipoprotein (a)[Lp (a)] may
be a potential causal, genetic, independent risk factor for cardiovascular disease (CVD). Lp …

Lipoprotein (a) an elusive cardiovascular risk factor

L Berglund, R Ramakrishnan - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Lipoprotein (a)[Lp (a)], is present only in humans, Old World nonhuman primates, and the
European hedgehog. Lp (a) has many properties in common with low-density lipoprotein …

[HTML][HTML] Lipoprotein (a): biology and clinical importance

SPA McCormick - The Clinical Biochemist Reviews, 2004 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)[Lp (a)] is a unique lipoprotein that has emerged as an independent
risk factor for developing vascular disease. Plasma Lp (a) levels above the common cut-off …

Lipoprotein (a): A missing culprit in the management of athero‐thrombosis?

G Ferretti, T Bacchetti, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Lipoprotein (a) Lp (a) is a cholesterol‐rich, LDL‐like particle that is independently
associated with an increased risk for ischemic heart disease, atherosclerosis, thrombosis …

[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene

S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Lipoprotein (a): a genetic risk factor for premature coronary heart disease

AM Scanu - JAMA, 1992 - jamanetwork.com
Lipoprotein (a)(Lp [a]) can be defined as a lipoprotein particle having as a protein moiety
apolipoprotein B-100 (the protein associated with low-density lipoprotein) disulfide-linked to …

[HTML][HTML] Lipoprotein (a)—the crossroads of atherosclerosis, atherothrombosis and inflammation

S Ugovšek, M Šebeštjen - Biomolecules, 2021 - mdpi.com
Increased lipoprotein (a)(Lp (a)) levels are an independent predictor of coronary artery
disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD …