Gustatory, like olfactory signalling is probably mediated by seven-transmembrane receptors
and coupling GTP-binding proteins (G proteins). We investigated the expression of a subset …

In the vertebrate taste cell, heterotrimeric guanine nucleotide‐binding proteins (G proteins)
are involved in the transduction of both bitter and sweet taste stimulants. The bitter …

In mammals, taste perception is a major mode of sensory input. We have identified a novel
family of 40–80 human and rodent G protein–coupled receptors expressed in subsets of …

G protein–coupled taste receptors include the type 1 taste receptor sweet and umami
receptors and the type 2 taste receptor bitter receptors, which are expressed in …

The recent application of molecular biological techniques to taste cells has led to the
identification and cloning of a number of proteins that are involved in signal transduction …

Chemoreception: Tasting the sweet and the bitter: Current Biology Skip to Main Content
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Bitter taste perception is a conserved chemical sense against the ingestion of poisonous
substances in mammals. It could be mediated by G protein-coupled receptors that need the …

The guanine nucleotide binding proteins (G proteins) mediate signal transduction in
olfactory, visual, hormonal and neurotransmitter systems (see Birnbaumer, 1990). The G …

We have reported on the partial structures of a multigene family encoding GTP-binding
protein (G protein)-coupled, seven-transmembrane receptors expressed in the tongue (Abe …

Previous studies have identified many cDNA species that encode a variety of G protein α-
subunits occurring in taste buds. These include the cDNA encoding a taste-bud-specific Gα …