Sialic acids are nine-carbon sugars that frequently cap glycans at the cell surface in cells of
vertebrates as well as cells of certain types of invertebrates and bacteria. The nine-carbon …

Sialic acids have a pivotal functional impact in many biological interactions such as virus
attachment, cellular adhesion, regulation of proliferation, and apoptosis. A common …

Sialic acids can be acetylated at the 4, 7, 8 and/or 9 position. Biological roles of these
substitutions have been missed until recently because of their low abundance and lability to …

9-O-Acetylation is a common natural modification on sialic acids (Sias) that terminate many
vertebrate glycan chains. This ester group has striking effects on many biological …

Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.
Natural existing sialic acid-containing structures are presented in different sialic acid forms …

Publisher Summary O-Acetylated sialic acids are often components of oligosaccharides or
polysaccharides, glycoproteins, and gangliosides from microorganisms, animals, and …

ABSTRACT O acetylation at carbon positions 7 or 9 of the sialic acid residues in the
polysialic acid capsule of Escherichia coli K1 is catalyzed by a phase-variable contingency …

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables
the reader to understand the role of sialylation as a post translational modification. The book …

Sialic acids, terminal sugars of glycoproteins and glycolipids, play important roles in
development, cellular recognition processes and host–pathogen interactions. A common …

Publisher Summary This chapter discusses the chemistry, metabolism, and biological
functions of sialic acids. Interest in the sialic acids has rapidly increased in recent years …