There is increasing interest in the clinical implications and immunology of trogocytosis, a
process in which the receptors on acceptor cells remove and internalize cognate ligands …

A specialized form of trogocytosis occurs when Fcγ receptors on acceptor cells take up and
internalize donor cell-associated immune complexes composed of specific monoclonal …

Antigenic modulation by trogocytosis during anti-CD20 mAb treatment with rituximab (RTX)
leads to loss of CD20 and therefore can compromise therapy. During trogocytosis, effector …

Exchange of plasma membrane fragments, including cell-surface proteins and lipids, in
conjugates formed between lymphocytes and their cellular partners is a field of intense …

Intercellular transfer of cell surface proteins by trogocytosis is common and could affect T cell
responses. Yet, the role of trogocytosis in T cell function is still elusive, and it is unknown …

Leukocytes can “gnaw away” the plasma membrane of other cells. This phenomenon, called
trogocytosis, occurs subsequent to cell‐to‐cell adhesion. Currently, two mechanisms of …

Understanding the complex behavior of effector cells such as monocytes or macrophages in
regulating cancerous growth is of central importance for cancer immunotherapy. Earlier …

Upon recognition of their respective cellular partners, T and B cells acquire their antigens by
a process of membrane capture called trogocytosis. Here, we report that various inhibitors of …

More than 20 years ago clinical investigations in the immunotherapy of cancer revealed that
infusion of certain immunotherapeutic mAbs directed to tumor cells induced loss of targeted …

While a high frequency of Th1 cells in tumors is associated with improved cancer prognosis,
this benefit has been attributed mainly to support of cytotoxic activity of CD8+ T cells. By …