The osteoprotegerin/receptor activator of nuclear factor κB/receptor activator of nuclear factor κB ligand system in cartilage
H Komuro, T Olee, K Kühn, J Quach… - … : Official Journal of …, 2001 - Wiley Online Library
Objective The receptor activator of nuclear factor κB (RANK) is a member of the tumor
necrosis factor receptor family. It is activated by the secreted or cell surface–bound RANK …
necrosis factor receptor family. It is activated by the secreted or cell surface–bound RANK …
[引用][C] The role of osteoprotegerin and receptor activator of nuclear factor κB ligand in the pathogenesis and treatment of rheumatoid arthritis
LC Hofbauer, AE Heufelder - Arthritis & Rheumatism: Official …, 2001 - Wiley Online Library
The skeletal complications of rheumatoid arthritis (RA) include focal bone erosions and
juxtaarticular osteopenia at sites of active inflammation, as well as systemic osteopenia …
juxtaarticular osteopenia at sites of active inflammation, as well as systemic osteopenia …
The expression of RANKL and OPG in the various grades of osteoarthritic cartilage
AR Upton, CA Holding, AA Dharmapatni… - Rheumatology …, 2012 - Springer
The objective of the study was to determine whether cartilage expression of the bone
regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and …
regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and …
[引用][C] The RANK/RANKL/osteoprotegerin system in rheumatoid arthritis: new insights from animal models
E Neumann, S Gay… - Arthritis & Rheumatism …, 2005 - Wiley Online Library
Rheumatoid arthritis (RA) is characterized by inflammatory synovitis and progressive
destruction of cartilage and bone. While the mechanisms of cartilage destruction in RA have …
destruction of cartilage and bone. While the mechanisms of cartilage destruction in RA have …
Biology of RANK, RANKL, and osteoprotegerin
BF Boyce, L Xing - Arthritis research & therapy, 2007 - Springer
The discovery of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK/
osteoprotegerin (OPG) system and its role in the regulation of bone resorption exemplifies …
osteoprotegerin (OPG) system and its role in the regulation of bone resorption exemplifies …
Cytokine‐controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast‐mediated pathologic bone resorption
M Tunyogi‐Csapo, K Kis‐Toth… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To determine whether proinflammatory cytokine treatment or the complete
absence of select cytokines modulates the expression of RANKL and osteoprotegerin (OPG) …
absence of select cytokines modulates the expression of RANKL and osteoprotegerin (OPG) …
RANKL, RANK, osteoprotegerin: key partners of osteoimmunology and vascular diseases
M Baud'Huin, F Lamoureux, L Duplomb… - Cellular and molecular …, 2007 - Springer
1997 saw the identification of a novel set of proteins within the tumor necrosis factor
(TNF)/TNF receptor families that are required for the control of bone remodeling. Therefore …
(TNF)/TNF receptor families that are required for the control of bone remodeling. Therefore …
Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis
E Romas, NA Sims, DK Hards, M Lindsay… - The American journal of …, 2002 - Elsevier
Rheumatoid arthritis is characterized by progressive synovial inflammation and joint
destruction. While matrix metalloproteinases (MMPs) are implicated in the erosion of …
destruction. While matrix metalloproteinases (MMPs) are implicated in the erosion of …
Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint
Objective. This study investigated the involvement of the recently identified regulators of
osteoclast formation RANKL [receptor activator of nuclear factor kappaB (RANK) ligand …
osteoclast formation RANKL [receptor activator of nuclear factor kappaB (RANK) ligand …
Osteoprotegerin and receptor activator of nuclear factor-kappaB ligand mRNA expression in patients with rheumatoid arthritis and healthy controls.
A Vanderborght, L Linsen, M Thewissen… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: To further understand the role of osteoprotegerin (OPG) and receptor activator
of nuclear factor-kappaB ligand (RANK-L) in rheumatoid arthritis (RA), we studied the levels …
of nuclear factor-kappaB ligand (RANK-L) in rheumatoid arthritis (RA), we studied the levels …