Activated human natural killer (NK) cells undergo rapid apoptotic cell death after ligand
binding to the Fc receptor (CD16). We examined whether human NK cells die after …

Propriocidal regulation of T cells refers to apoptosis induced by interleukin 2 (IL-2) activation
with subsequent antigen receptor stimulation. We examined whether natural killer (NK) cells …

Propriocidal regulation of T cells refers to apoptosis induced by interleukin‐2 (IL‐2)
activation with subsequent antigen receptor stimulation. We previously reported that natural …

It has been previously shown that the subset of human natural killer (NK) cells which
express CD8 in a homodimeric α/α form are more cytotoxic than their CD8–counterparts but …

We previously reported that natural killer (NK)-sensitive target cells, K562, kill interleukin-2-
stimulated (lymphokine-activated killer [LAK]) but not unstimulated NK cells. We have now …

Both T cells and natural killer (NK) cells express CD2, the target of an alternative activation
pathway that induces the proliferation of both cell types. The mitogenic response to CD2 …

Abstract Interferon-γ (IFN-γ) is critical for an effective innate immune response against
infection. A combination of interleukins (ILs) derived from activated T cells (IL-2) and …

Human natural killer cells (NK) respond to interleukin-2 (IL-2) with augmented cytolytic
activity, cytokine secretion and cell proliferation. Here we show that IL-2 protects NK cells …

Interaction of sensitive target cells with NK cells results in both positive and negative
signaling. Positive signaling results in the induction of NK cytotoxicity and sensitization for IL …

We provide evidence that tumor cells can induce apoptosis of NK cells by engaging the
natural cytotoxicity receptors (NCR) NKp30, NKp44, and NKp46. Indeed, the binding …