Effects of temperature, pH and counterions on the stability of peptide amphiphile nanofiber structures

AD Ozkan, AB Tekinay, MO Guler, ED Tekin - RSC advances, 2016 - pubs.rsc.org
Peptide amphiphiles are a class of self-assembling molecules that are widely used to form
bioactive nanostructures for various applications in bionanomedicine. However, peptide …

Solvent effects on kinetic mechanisms of self-assembly by peptide amphiphiles via molecular dynamics simulations

IW Fu, CB Markegard, HD Nguyen - Langmuir, 2015 - ACS Publications
Peptide amphiphiles are known to form a variety of distinctive self-assembled
nanostructures (including cylindrical nanofibers in hydrogels) dependent upon the solvent …

Role of hydrophobicity on self-assembly by peptide amphiphiles via molecular dynamics simulations

IW Fu, CB Markegard, BK Chu, HD Nguyen - Langmuir, 2014 - ACS Publications
Using a novel coarse-grained model, large-scale molecular dynamics simulations were
performed to examine self-assembly of 800 peptide amphiphiles (sequence palmitoyl …

Hofmeister effects on peptide amphiphile nanofiber self-assembly

A Iscen, GC Schatz - The Journal of Physical Chemistry B, 2019 - ACS Publications
Self-assembled peptide amphiphile (PA) nanofibers have emerged as bio-inspired materials
with numerous applications in nanotechnology. However, environmental variables, such as …

High-resolution insights into the stepwise self-assembly of nanofiber from bioactive peptides

F Sun, L Chen, X Ding, L Xu, X Zhou… - The Journal of …, 2017 - ACS Publications
Peptide self-assembly has a profound biological significance since self-assembled bioactive
peptides are gifted with improved bioactivity as well as life-span. In this study, peptide self …

Probing the self-assembly mechanism of diphenylalanine-based peptide nanovesicles and nanotubes

C Guo, Y Luo, R Zhou, G Wei - ACS nano, 2012 - ACS Publications
Nanostructures, particularly those from peptide self-assemblies, have attracted great
attention lately due to their potential applications in nanotemplating and nanotechnology …

Urea-modified self-assembling peptide amphiphiles that form well-defined nanostructures and hydrogels for biomedical applications

H Xing, A Rodger, J Comer, AS Picco… - ACS Applied Bio …, 2022 - ACS Publications
Hydrogen bonding plays a critical role in the self-assembly of peptide amphiphiles (PAs).
Herein, we studied the effect of replacing the amide linkage between the peptide and lipid …

Structural polymorphism in a self-assembled tri-aromatic peptide system

N Brown, J Lei, C Zhan, LJW Shimon… - ACS …, 2018 - ACS Publications
Self-assembly is a process of key importance in natural systems and in nanotechnology.
Peptides are attractive building blocks due to their relative facile synthesis, biocompatibility …

Designed peptides as model self-assembling nanosystems: characterization and potential biomedical applications

JJ Panda, A Kaul, S Alam, AK Babbar… - Therapeutic …, 2011 - Taylor & Francis
Synthesis of nanomaterials via 'molecular self-assembly 'allows one to define the properties
of the nanomaterial by rational design of the individual constituents. Use of peptides for self …

Stability of nanopeptides: structure and molecular exchange of self-assembled peptide fibers

N König, SM Szostak, JE Nielsen, M Dunbar… - ACS …, 2023 - ACS Publications
Often nanostructures formed by self-assembly of small molecules based on hydrophobic
interactions are rather unstable, causing morphological changes or even dissolution when …