Extracellular vesicles: illuminating renal pathophysiology and therapeutic frontiers

L Shi, H Zeng, Z An, W Chen, Y Shan, C Ji… - European Journal of …, 2024 - Elsevier
Extracellular vesicles (EVs) are minute sacs released by cells into the extracellular milieu,
harboring an array of biomolecules including proteins, nucleic acids, and lipids. Notably, a …

Emerging role of extracellular vesicles in kidney diseases

H Xiang, C Zhang, J Xiong - Frontiers in Pharmacology, 2022 - frontiersin.org
Many types of renal disease eventually progress to end-stage renal disease, which can only
be maintained by renal replacement therapy. Therefore, kidney diseases now contribute …

Extracellular vesicles: opportunities and challenges for the treatment of renal diseases

TT Tang, LL Lv, HY Lan, BC Liu - Frontiers in physiology, 2019 - frontiersin.org
Extracellular vesicles (EVs) are lipid-based membrane-bound particles secreted by virtually
all types of cells under both physiological and pathological conditions. Given their unique …

Extracellular vesicles in renal pathophysiology

MAC Pomatto, C Gai, B Bussolati… - Frontiers in molecular …, 2017 - frontiersin.org
Extracellular vesicles are a heterogeneous population of microparticles released by virtually
all living cells which have been recently widely investigated in different biological fields …

Extracellular vesicles as a therapeutic tool for kidney disease: current advances and perspectives

RR Corrêa, EM Juncosa, R Masereeuw… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) have been described as important mediators of cell
communication, regulating several physiological processes, including tissue recovery and …

Extracellular vesicles in diagnosis and therapy of kidney diseases

W Zhang, X Zhou, H Zhang, Q Yao… - American Journal of …, 2016 - journals.physiology.org
Extracellular vesicles (EV) are endogenously produced, membrane-bound vesicles that
contain various molecules. Depending on their size and origins, EVs are classified into …

Novel aspects of extracellular vesicles in the regulation of renal physiological and pathophysiological processes

JP Rigalli, ER Barros, V Sommers… - Frontiers in Cell and …, 2020 - frontiersin.org
Extracellular vesicles (EV) are nanosized particles released by a large variety of cells. They
carry molecules such as proteins, RNA and lipids. While urinary EVs have been longer …

Extracellular Vesicle Biomarkers for Renal Diseases

LL Lv, AR Shen, TT Tang, H Zou, X Li - Extracellular Vesicles: From Bench …, 2024 - Springer
Extracellular vesicles (EVs) are emerging as a new mechanism of intercellular
communication in renal disease. EVs originating from the renal system can be readily …

Extracellular vesicles in renal disease

D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

Extracellular vesicles and acute kidney injury: potential therapeutic avenue for renal repair and regeneration

M Kosanović, B Milutinovic, S Glamočlija… - International journal of …, 2022 - mdpi.com
Acute kidney injury (AKI) is a sudden decline of renal function and represents a global
clinical problem due to an elevated morbidity and mortality. Despite many efforts, currently …