Dissolution behavior and thermodynamic properties of apixaban in pure and mixed solvents

C Du, Y Cong, Y Zhang, Y Xue, B Qiao, T Ye… - The Journal of Chemical …, 2020 - Elsevier
The solubility profile of apixaban in pure and mixed solvents within the temperature range
from (288.15 to 328.15) K under atmosphere pressure (101.3 kPa) was studied and …

Apixaban (I) in several aqueous co-solvent mixtures: Solubility, solvent effect and preferential solvation

H Li, A Farajtabar, Y Xie, Z Li, H Zhao - The Journal of Chemical …, 2020 - Elsevier
Equilibrium apixaban (I) solubility in isopropanol (1)+ water (2), ethanol (1)+ water (2),
acetone (1)+ water (2) and methanol (1)+ water (2) mixtures was acquired by a shake-flask …

Measurement and correlation of solubility of rivaroxaban in dichloromethane and primary alcohol binary solvent mixtures at different temperatures

JS Jeong, ES Ha, H Park, SK Lee, JS Kim… - Journal of Molecular …, 2022 - Elsevier
The solubility of rivaroxaban in different solvent mixtures consisting of dichloromethane and
primary alcohols, including methanol, ethanol, n-propanol, and n-butanol, was evaluated …

Co-solvence phenomenon and thermodynamic properties of edaravone in pure and mixed solvents

R Li, L Yao, A Khan, B Zhao, D Wang, J Zhao… - The Journal of Chemical …, 2019 - Elsevier
The dissolution behavior of drugs in cosolvent mixtures is very important, especially in
systems with co-solvence phenomenon. The solubility of edaravone in pure and mixed …

Solubility measurement, model evaluation and thermodynamic analysis of rivaroxaban polymorphs in organic solvents

J Zhai, Z Chen, X Liu, L Zhang, J Lu - The Journal of Chemical …, 2017 - Elsevier
This work measured the solubility of forms I and II of anticoagulant drug rivaroxaban in a
series of organic solvents in which the solubility of form II was firstly reported as …

Solubility enhancement, solvent effect and thermodynamic analysis of pazopanib in co-solvent mixtures

H Shi, Y Xie, J Xu, J Zhu, C Wang, H Wang - The Journal of Chemical …, 2021 - Elsevier
As is known to all, co-solvency or solvent mixing is the most common and easy-to-use
method in the pharmaceutical industry for the improvement of solubility of poorly soluble …

Measurement and correlation of the solubility of rivaroxaban (form I) in binary mixtures of ethyl acetate with tetrahydrofuran, N, N-dimethylformamide, and N, N …

M Zhang, Z Fang, J Zhai, S Mao, L Zhang… - The Journal of Chemical …, 2016 - Elsevier
In this work, the solubility of rivaroxaban (form I) in binary solvent mixtures of ethyl acetate
(EA) with N, N-dimethylformamide (DMF), N, N-dimethylacetamide (DMA) and …

Solubility of naftopidil in pure and mixed solvents at 273.15–313.15 K and its correlation with the Jouyban-Acree and CNIBS/RK models

R Li, T Tang, X Yin, L Yao, Z Lin, L Zhang, X Gao… - The Journal of Chemical …, 2020 - Elsevier
The dissolution behavior of naftopidil in methanol, ethanol, ethyl acetate, toluene, acetone,
acetonitrile and two mixtures of (ethyl acetate+ methanol) and (ethyl acetate+ ethanol) was …

Cosolvent effect on solubility of aripiprazole in mixed solvents and apparent thermodynamic analysis of dissolution process

Y Wu, L Cheng, J Wu, M Zhai, L Cai - The Journal of Chemical …, 2019 - Elsevier
Due to different polymorphs demonstrate significant variations in the drug properties such as
solubility, stability and dissolution rate. In this work, we study the shape of the solubility …

Measurement and correlation of solubility data for albendazole in ten pure solvents and two binary solvent systems from 278.15 K to 323.15 K

Y Wu, Y Chen, K Xu, N Li, H Fu, X Wang, F Xu… - Sustainable Chemistry …, 2022 - Elsevier
The equilibrium solubility of albendazole (ABZ) in ten single solvents and two binary solvent
mixtures of different ratio was measured by a typical static method combined with ultraviolet …