[HTML][HTML] Abscopal Effect on Bone Metastases from Solid Tumors: A Systematic Review and Retrospective Analysis of Challenge within a Challenge

M Tomaciello, M Conte, FR Montinaro, A Sabatini… - Biomedicines, 2023 - mdpi.com
Background: Abscopal effect (AE) describes the ability of radiotherapy (RT) to induce
immune-mediated responses in nonirradiated distant metastasis. Bone represents the third …

[HTML][HTML] Trends in the abscopal effect after radiation to spinal metastases: a systematic review

M Macki, M Fakih, J Elmenini, SK Anand, AM Robin - Cureus, 2019 - ncbi.nlm.nih.gov
While the abscopal effect has been previously described, the phenomenon has been poorly
defined in the case of spinal metastases. This article is unique in that we present the first …

The abscopal effect: systematic review in patients with brain and spine metastases

DJ Pangal, B Yarovinsky, T Cardinal… - Neuro-Oncology …, 2022 - academic.oup.com
Background The abscopal effect is a rare phenomenon whereby local radiation induces a
proposed immune-mediated anti-tumor effect at distant sites. Given the growing use of …

Abscopal effect of radiation on bone metastases of breast cancer: A case report

HWC Leung, SY Wang, H Jin-Jhih… - Cancer biology & …, 2018 - Taylor & Francis
The abscopal effect is defined as the clearance of distant tumors after applying localized
irradiation to a particular tumor site. It has been proposed that a mechanism for the abscopal …

Abscopal Effect: An Old Concept with a New Horizon.

AN Abbasi, HK AM, MA Mansha, F Shaukat… - The Gulf Journal of …, 2021 - europepmc.org
Abscopal effect is defined as a phenomenon where radiation delivery at one site induces
shrinkage of disease at a distant site, outside the radiation field. Although it is an old concept …

[HTML][HTML] Abscopal effect, from myth to reality: from radiation oncologists' perspective

MT Yilmaz, A Elmali, G Yazici - Cureus, 2019 - ncbi.nlm.nih.gov
The abscopal effect is mediated by a systemic anti-tumor immune response and reflects the
regression of non-irradiated metastatic lesions at a distance from the primary site of …

[HTML][HTML] Abscopal effect in the radio and immunotherapy

AM Pevzner, MM Tsyganov… - Radiation Oncology …, 2021 - ncbi.nlm.nih.gov
This review is devoted to a rare in clinical practice, but promising phenomenon of regression
distant non-irradiated metastases in combination therapy of cancer patients. RH Mole in …

[HTML][HTML] Radiation therapy and the abscopal effect: a concept comes of age

J Ng, T Dai - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
The concept of utilizing localized radiation therapy to elicit out-of-target tumor responses—
the abscopal effect—was proposed over 50 years ago (1, 2). Over the past decades, the …

Radiotherapy and the abscopal effect: insight from the past, present, and future

AC Chen, EB Butler, SS Lo, BS Teh - Journal of radiation oncology, 2015 - Springer
The abscopal effect is a rare phenomenon in radiation oncology where radiotherapy has a
therapeutic effect at a distance from the intended treatment field. This effect has resulted in …

[HTML][HTML] A patient-level data meta-analysis of the abscopal effect

SJ Hatten Jr, EJ Lehrer, J Liao, MS Congzhou… - Advances in Radiation …, 2022 - Elsevier
Purpose The abscopal effect is defined when a form of local therapy causes tumor
regression of both the target lesion and any untreated tumors. Herein cases of the abscopal …