Familial atrial fibrillation is a genetically heterogeneous disorder
D Darbar, KJ Herron, JD Ballew, A Jahangir… - Journal of the American …, 2003 - jacc.org
Objectives: The aims of this study were to identify and characterize familial cases of atrial
fibrillation (AF) in our clinical practice and to determine whether AF is genetically …
fibrillation (AF) in our clinical practice and to determine whether AF is genetically …
Locus for atrial fibrillation maps to chromosome 6q14–16
PT Ellinor, JT Shin, RK Moore, DM Yoerger… - Circulation, 2003 - Am Heart Assoc
Background—Atrial fibrillation (AF), the most common clinical arrhythmia, is a major cause of
morbidity and mortality. Although AF is often associated with other cardiovascular …
morbidity and mortality. Although AF is often associated with other cardiovascular …
Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation
MD Ritchie, S Rowan, G Kucera, T Stubblefield… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to test the hypothesis that 2 common polymorphisms in
the chromosome 4q25 region that have been associated with atrial fibrillation (AF) contribute …
the chromosome 4q25 region that have been associated with atrial fibrillation (AF) contribute …
Identification of a genetic locus for familial atrial fibrillation
R Brugada, T Tapscott… - … England Journal of …, 1997 - Mass Medical Soc
Background Atrial fibrillation, the most common sustained cardiac-rhythm disturbance,
affects over 2 million Americans and accounts for one third of all strokes in patients over 65 …
affects over 2 million Americans and accounts for one third of all strokes in patients over 65 …
Genetics of atrial fibrillation: from families to genomes
IE Christophersen, PT Ellinor - Journal of human genetics, 2016 - nature.com
Atrial fibrillation (AF) is the most common cardiac rhythm disorder and the prevalence is
increasing. The disease confers an increased risk of severe complications such as heart …
increasing. The disease confers an increased risk of severe complications such as heart …
Risk factors and genetics of atrial fibrillation
JMB Anumonwo, J Kalifa - Heart failure clinics, 2016 - heartfailure.theclinics.com
AF is by far the most common sustained tachyarrhythmia. Lifetime risks for development of
AF are approximately 1 in 4 for men and women 40 years of age and older. 1, 2 This …
AF are approximately 1 in 4 for men and women 40 years of age and older. 1, 2 This …
Genetics of atrial fibrillation: state of the art in 2017
Genetic variation is an important determinant of atrial fibrillation (AF) susceptibility.
Numerous rare variants in protein-coding sequences of genes have been associated with …
Numerous rare variants in protein-coding sequences of genes have been associated with …
Genetics of atrial fibrillation: implications for future research directions and personalized medicine
Atrial fibrillation (AF) was first described in humans approximately 100 years ago, 1 and
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
Monogenic atrial fibrillation as pathophysiological paradigms
Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major
burden, both to patients and to health-care systems. In recent years, increasing evidence …
burden, both to patients and to health-care systems. In recent years, increasing evidence …
Genetics of atrial fibrillation
J Feghaly, P Zakka, B London, CA MacRae… - Journal of the …, 2018 - Am Heart Assoc
Background Atrial fibrillation (AF) is a common arrhythmia seen in clinical practice.
Occasionally, no common risk factors are present in patients with this arrhythmia. This …
Occasionally, no common risk factors are present in patients with this arrhythmia. This …