On the basis of our previous structure–activity relationship (SAR) and antiviral mechanism
studies, a series of phenanthroindolizidines and their analogues 3–20 were designed …

Based on our previous structure–activity relationship and antiviral mechanism studies, a
series of 14-aminophenanthroindolizidines (1a–i, 2, and 3) were designed, targeting …

To investigate the influence of the variation of the original skeletons of natural
phenanthroindo/quinolizidine alkaloids on antiviral activities, two types of structurally totally …

Racemic phenanthroindolizidine alkaloids tylophorine, antofine, and deoxytylophorinine,
and optically pure alkaloids S-(+)-tylophorine and R-(−)-tylophorine were synthesized and …

To study the influence of the substituent at the N-10 position on antiviral activity, the chiral
quaternary ammonium salt derivatives of R-and S-tylophorine were designed, synthesized …

On the basis of our previous studies on the antiviral mechanism against tobacco mosaic
virus (TMV) and structure–activity relationship of phenanthroindolizidine alkaloids, a series …

On the basis of our previous structure–activity relationship (SAR) and antiviral mechanism
studies, a series of 13a-substituted phenanthroindolizidine alkaloid analogues (3a–16a, 3b …

BACKGROUND The phenanthroindolizidine alkaloid antofine and its analogues have
excellent antiviral activity against tobacco mosaic virus (TMV). To simplify the structure and …

Our recent investigation on the antiviral activities against tobacco mosaic virus (TMV) of
phenanthroindolizidine alkaloid analogues preliminarily revealed that the basic skeleton …

On the basis of our previous structure–activity relationship (SAR) and antiviral mechanism
studies, a series of phenanthrene-based antofine derivatives (1–12 and 18–50) were …