Throughout the world, ethanol is both an important commercial commodity and a source of
major medical and social problems. Ethanol readily passes through biological membranes …

In this review first we evaluate evidence on the role of the neurobiological alterations
induced by chronic ethanol consumption in the development of ethanol tolerance …

In this review we will focus on several aspects of ethanol pharmacology. We shall begin with
a brief overview of ethanol pharmacokinetics. This is followed by a more detailed …

The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time
from considering this level of intake to be nonintoxicating and noninjurious, to …

Alcohol dependence is considered to be divisible into two types (although the divisions
between these are indistinct). These are psychological dependence, in which the rewarding …

ALCOHOLISM is a major social, economic, and public health problem throughout much of
the world. In the United States alone, the annual cost of lost productivity and health …

This review describes the effects of ethanol on the components of neuronal transmission
and the relationship of such effects to the behavioural actions of ethanol. The concentrations …

Ethanol exerts its behavioral effects largely by interacting with receptors to brain
neurotransmitters. The molecular mechanisms involving these interactions are still not well …

OBJECTIVE: Neurophysiological and pathological effects of ethanol may be mediated, to an
important extent, via the glutamatergic system. Animal studies indicate the acute effects of …

Alcoholism, a worldwide disorder, is the cause of a variety of neurologic disorders. In this
article we discuss the cellular pathophysiology of ethanol addition and abuse as well as …