Ecotropic viral integration site 1 (Evi1) was discovered in 1988 as a common site of
ecotropic viral integration resulting in myeloid malignancies in mice. EVI1 is an oncogenic …

Ecotropic viral integration site-1 (EVI-1) has been recognized as one of the dominant
oncogenes associated with murine and human myeloid leukemia. Recent clinical studies …

Simple Summary Ecotropic viral integration site 1 (EVI1) is transcriptionally activated in a
subset of myeloid leukemias. Since its discovery, other isoforms of EVI1 have been …

The ecotropic viral integration site‐1 (Evi‐1) gene was first identified as a common locus of
retroviral integration in murine leukemia models. In humans, EVI‐1 is located on …

Abstract Background The transcription factor Ecotropic Virus Integration site 1 (EVI1)
regulates cellular proliferation, differentiation, and apoptosis, and its overexpression …

The ecotropic viral integration site 1 (EVI1) gene was identified almost 20 years ago as the
integration site of an ecotropic retrovirus leading to murine myeloid leukemia. Since its …

Recent studies have demonstrated the significance of the leukemia oncogene Evi1 as the
regulator of hematopoietic stem cells and marker of poor clinical outcomes in myeloid …

The transcriptional regulator ecotropic viral integration site-1 (EVI-1) has mainly been
studied for its role in myeloid malignancies, in which high EVI-1 levels are associated with …

Evi1 (ecotropic viral integration site 1) is essential for proliferation of hematopoietic stem
cells and implicated in the development of myeloid disorders. Particularly, high Evi1 …

Background and Aim: Overexpression of ecotropic viral integration site 1 (EVI1) is
associated with aggressive disease in myeloid leukemia. We therefore studied its …