High-density lipoprotein metabolism: potential therapeutic targets

MH Davidson, PP Toth - The American journal of cardiology, 2007 - Elsevier
It is well recognized that the lowering of low-density lipoprotein (LDL) cholesterol can
substantially reduce coronary artery disease (CAD)–related morbidity and mortality. The …

[HTML][HTML] Pathophysiology and management of low high-density lipoprotein cholesterol

DJ Rader - The American journal of cardiology, 1999 - Elsevier
Low levels of high-density lipoprotein (HDL) cholesterol are associated with an increased
risk of coronary artery disease events. Data in animals indicate that increasing HDL …

[图书][B] High-density lipoproteins: structure, metabolism, function and therapeutics

A Kontush, MJ Chapman - 2011 - books.google.com
A complete guide to the role of high-density lipoproteins (HDL) in new and emerging
therapies With high-density lipoproteins (HDL) playing an increasing role in cardiovascular …

High-density lipoprotein as a therapeutic target: clinical evidence and treatment strategies

PP Toth - The American journal of cardiology, 2005 - Elsevier
The clinical importance of low serum levels of high-density lipoprotein (HDL) cholesterol is
often under-recognized and underappreciated as a risk factor for premature atherosclerosis …

High-density lipoprotein cholesterol and triglycerides as therapeutic targets for preventing and treating coronary artery disease

AM Gotto Jr - American heart journal, 2002 - Elsevier
Epidemiologic and clinical trials show that elevated triglycerides and low levels of high-
density lipoprotein cholesterol (HDL-C) are independent risk factors for coronary heart …

Regulation of high-density lipoprotein metabolism

KA Rye, PJ Barter - Circulation research, 2014 - Am Heart Assoc
There is compelling evidence from human population studies that plasma levels of high-
density lipoprotein (HDL) cholesterol correlate inversely with cardiovascular risk …

Novel targets that affect high-density lipoprotein metabolism: the next frontier

MH Davidson, RS Rosenson - The American journal of cardiology, 2009 - Elsevier
As the significance of treating coronary artery disease (CAD) remains a high priority in
reducing morbidity and mortality worldwide, newer treatment strategies continue to evolve …

[图书][B] Introduction to High-Density Lipoprotein, Dyslipidemia, and Coronary Heart Disease

EJ Schaefer - 2010 - Springer
Alterations in plasma lipoproteins are major risk factors for coronary heart disease caused
by atherosclerosis. The purpose of this chapter is to provide the reader with an overview of …

[图书][B] High-density lipoproteins: from basic biology to clinical aspects

CJ Fielding - 2008 - books.google.com
This book meets the long-awaited need for a comprehensive overview of the biological role
of HDLs. Edited by one of the pioneers in HDL and cholesterol research, this monograph …

[HTML][HTML] High-density lipoprotein: a double-edged sword in cardiovascular physiology and pathophysiology

G Ndrepepa - Journal of Laboratory and Precision Medicine, 2021 - jlpm.amegroups.org
High-density lipoprotein (HDL) plays a central role in vascular biology. HDL participates in
multiple pathways that may be involved in the development of atherosclerosis and coronary …