Functional assessment of HDL: moving beyond static measures for risk assessment

RS Rosenson - Cardiovascular drugs and therapy, 2010 - Springer
Residual cardiovascular risk associated with low levels of HDL was a major theme at the
American Heart Association's 2009 Scientific Sessions. The presentations on HDL biology …

High-density lipoprotein therapeutics and cardiovascular prevention

S Fazio, MRF Linton - Journal of clinical lipidology, 2010 - Elsevier
The field of cardiovascular prevention has long anticipated the evolution of high-density
lipoprotein (HDL) therapy from unproven metabolic tweaking to pillar of risk reduction on par …

High-density lipoproteins: marker of cardiovascular risk and therapeutic target

PP Toth, MH Davidson - Journal of clinical lipidology, 2010 - Elsevier
The high-density lipoproteins (HDLs) are complex, polymolecular assemblies produced by
the jejunum, liver, in serum, and on the surface of macrophages. HDL cholesterol (HDL-C) …

Treating high density lipoprotein cholesterol (HDL-C): quantity versus quality

A Pirillo, G Danilo Norata… - Current pharmaceutical …, 2013 - ingentaconnect.com
Low density lipoproteins (LDL) and high density lipoproteins (HDL) are independent risk
factors for coronary heart disease (CHD); decreasing LDL-cholesterol (LDL-C) levels with …

Spotlight on HDL biology: new insights in metabolism, function, and translation

DJ Rader - Cardiovascular Research, 2014 - academic.oup.com
High-density lipoproteins (HDLs) have captured the imagination of scientists and physicians
from virtually the time they were originally described, but especially after the cholesterol …

Determinants of plasma HDL concentrations and reverse cholesterol transport

GF Lewis - Current opinion in cardiology, 2006 - journals.lww.com
Our understanding of the in-vivo metabolism of HDL particles and their role in reverse
cholesterol transport is rapidly evolving, with long-standing concepts being constantly …

[引用][C] Lipid and lipoprotein disorders

AM Gotto Jr - Primer in Preventive Cardiology, 1994 - Dallas, Texas: American Heart …

Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy

Y Lin, SS Mousa, N Elshourbagy… - Vascular Health and Risk …, 2010 - Taylor & Francis
Current lipid management guidelines are focused on decreasing low-density lipoprotein
(LDL-C) levels as the primary target for reducing coronary heart disease (CHD) risk. Yet …

Comprehensive lipid management versus aggressive low-density lipoprotein lowering to reduce cardiovascular risk

RH Knopp, P Paramsothy, B Atkinson… - The American journal of …, 2008 - Elsevier
Five lines of evidence justify comprehensive lipoprotein management over aggressive low-
density lipoprotein (LDL) lowering alone in most cases of cardiovascular disease (CVD) …

Low-density lipoprotein cholesterol reduction and cardiovascular disease prevention: the search for superior treatment

PH Jones - The American journal of medicine, 2004 - Elsevier
Current US lipid-lowering guidelines indicate that optimal plasma levels of low-density
lipoprotein cholesterol (LDL-C) are< 100 mg/dL, and targeting global risk assessment has …