Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease

SE Counts, SE Perez, U Kahl, T Bartfai… - CNS Drug …, 2001 - Wiley Online Library
The neuropeptide galanin (GAL) is widely distributed in the mammalian CNS. Several lines
of evidence suggest that GAL may play a critical role in cognitive processes such as memory …

Galanin–25 years with a multitalented neuropeptide: Galanin in Alzheimer's disease: Neuroinhibitory or neuroprotective?

SE Counts, SE Perez, EJ Mufson - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin (GAL) and GAL receptors (GALRs) are overexpressed in degenerating brain
regions associated with cognitive decline in Alzheimer's disease (AD). The functional …

[HTML][HTML] Galanin in Alzheimer disease

SE Counts, SE Perez, SD Ginsberg… - Molecular …, 2003 - triggered.edina.clockss.org
Galanin (GAL) and GAL receptors (GALR) are overexpressed in limbic brain regions
associated with cognition in Alzheimer disease (AD). The functional consequences of this …

Neuroprotective role for galanin in Alzheimer's disease

SE Counts, SE Perez, SD Ginsberg, EJ Mufson - Galanin, 2010 - Springer
Galanin (GAL) and GAL receptors (GALR) are overexpressed in degenerating brain regions
associated with cognitive decline in Alzheimer's disease (AD). The functional consequences …

Galanin Expression within the Basal Forebrain in Alzheimer's Disease: Comments on Therapeutic Potentiala

EJ Mufson, U Kahl, R Bowser, DC Mash… - Annals of the New …, 1998 - Wiley Online Library
The inhibitory neuropeptide galanin has widespread distribution throughout the central
nervous system. Studies indicate that galanin modulates cognition by regulating cholinergic …

Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

RA Steiner, JG Hohmann, A Holmes… - Proceedings of the …, 2001 - National Acad Sciences
Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and
memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate …

Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice

EJ Mufson, SE Counts, SE Perez, L Binder - Neuropeptides, 2005 - Elsevier
Galanin (GAL) is a biologically active 29 amino acid (30 in humans) which participates in the
modulation of several ascending neurotransmitter systems including cholinergic basal …

Galanin–25 years with a multitalented neuropeptide: Galanin impairs cognitive abilities in rodents: relevance to Alzheimer's Disease

JN Crawley - Cellular and Molecular Life Sciences, 2008 - Springer
The neuropeptide galanin and its receptors are localized in brain pathways mediating
learning and memory. Central microinjection of galanin impairs performance of a variety of …

Galanin impairs cognitive abilities in rodents: relevance to Alzheimer's disease

JN Crawley - Galanin, 2010 - Springer
The neuropeptide galanin and its receptors are localized in brain pathways that mediate
learning and memory. Central microinjection of galanin impairs performance of a variety of …

Galanin inhibits performance on rodent memory tasks

MP McDONALD, TC Gleason… - Annals of the New …, 1998 - Wiley Online Library
Central administration of galanin produces performance deficits on a variety of rodent
learning and memory tasks. Galanin impairs acquisition and/or retention of the Morris water …