Neurogenesis within the adult hippocampus is modulated by endogenous and exogenous
factors. Here, we review the role of sex hormones in the regulation of adult hippocampal …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

Sex differences in the function of the hippocampus have been observed in numerous
mammalian species. However, the magnitude, extent, and specificity of these differences are …

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic
branching, myelination and other important mechanisms of neural plasticity. Here we review …

Gonadal hormones modulate neurogenesis in the dentate gyrus differentially in male and
female adult rodents. Neurogenesis is comprised of at least two components: cell …

Brain sexual differentiation in mammals requires activity of gonadal hormones;
organizational effects of these steroids on brain development occur early in life while …

Aging is associated with compromised hippocampal function and reduced adult
neurogenesis in the dentate gyrus. As new neurons have been linked to hippocampal …

The hippocampus is central to spatial learning and stress responsiveness, both of which
differ in form and function in males versus females, yet precisely how the hippocampus …

This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

In several species, including rat and vole, the proliferation of new neurons in the adult
dentate gyrus (DG) subgranular zone (SGZ) is influenced by both gender and endogenous …