DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function
SG Nair, NS Strand, JF Neumaier - Brain research, 2013 - Elsevier
The lateral habenula (LHb) is part of the habenular complex in the dorsal diencephalon. The
LHb is an important regulator of several neurotransmitter systems in the midbrain; …
LHb is an important regulator of several neurotransmitter systems in the midbrain; …
Disentangling neuronal inhibition and inhibitory pathways in the lateral habenula
The lateral habenula (LHb) is hyperactive in depression, and thus potentiating inhibition of
this structure makes an interesting target for future antidepressant therapies. However, the …
this structure makes an interesting target for future antidepressant therapies. However, the …
The role of the habenula in drug addiction
KM Velasquez, DL Molfese, R Salas - Frontiers in human …, 2014 - frontiersin.org
Interest in the habenula has greatly increased in recent years. The habenula is a small brain
structure located posterior to the thalamus and adjacent to the third ventricle. Despite its …
structure located posterior to the thalamus and adjacent to the third ventricle. Despite its …
The role of the habenula in the transition from reward to misery in substance use and mood disorders
The habenula (Hb) is an evolutionary well-conserved structure located in the epithalamus.
The Hb receives inputs from the septum, basal ganglia, hypothalamus, anterior cingulate …
The Hb receives inputs from the septum, basal ganglia, hypothalamus, anterior cingulate …
A GABAergic cell type in the lateral habenula links hypothalamic homeostatic and midbrain motivation circuits with sex steroid signaling
The lateral habenula (LHb) has a key role in integrating a variety of neural circuits
associated with reward and aversive behaviors. There is limited information about how the …
associated with reward and aversive behaviors. There is limited information about how the …
Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin
The lateral habenula (LHb) has recently been identified as a key regulator of the reward
system by driving inhibition onto dopaminergic neurons. However, the nature and potential …
system by driving inhibition onto dopaminergic neurons. However, the nature and potential …
The role of the medial habenula cholinergic system in addiction and emotion-associated behaviors
HW Lee, SH Yang, JY Kim, H Kim - Frontiers in psychiatry, 2019 - frontiersin.org
The habenula is a complex nucleus composed of lateral and medial subnuclei, which
connect between the limbic forebrain and midbrain. Over the past few years, the lateral …
connect between the limbic forebrain and midbrain. Over the past few years, the lateral …
Translating the habenula—from rodents to humans
The habenula (Hb) is a central structure connecting forebrain to midbrain regions. This
microstructure regulates monoaminergic systems, notably dopamine and serotonin, and …
microstructure regulates monoaminergic systems, notably dopamine and serotonin, and …
A major role for the lateral habenula in depressive illness: physiologic and molecular mechanisms
Emerging preclinical and clinical evidence indicate that the lateral habenula plays a major
role in the pathophysiology of depressive illness. Aberrant increases in neuronal activity in …
role in the pathophysiology of depressive illness. Aberrant increases in neuronal activity in …
The medial habenula: still neglected
H Viswanath, AQ Carter, PR Baldwin… - Frontiers in human …, 2014 - frontiersin.org
The habenula is a small, bilateral brain structure located at the dorsal end of the
diencephalon. This structure sends projections to the dopaminergic striatum and receives …
diencephalon. This structure sends projections to the dopaminergic striatum and receives …