[HTML][HTML] Recent findings related to cardiomyopathy and genetics

T Yamada, S Nomura - International Journal of Molecular Sciences, 2021 - mdpi.com
With the development and advancement of next-generation sequencing (NGS), genetic
analysis is becoming more accessible. High-throughput genetic studies using NGS have …

Genetics of dilated cardiomyopathy: clinical implications

A Paldino, G De Angelis, M Merlo, M Gigli… - Current cardiology …, 2018 - Springer
Abstract Purpose of Review This review aims to summarize the current knowledge on the
genetic background of dilated cardiomyopathy (DCM), with particular attention to the …

Genetic cardiomyopathies causing heart failure

TJ Cahill, H Ashrafian, H Watkins - Circulation research, 2013 - Am Heart Assoc
Despite the striking advances in medical and surgical therapy, the morbidity, mortality, and
economic burden of heart failure (HF) remain unacceptably high. There is increasing …

Epidemiology and clinical aspects of genetic cardiomyopathies

D Masarone, JP Kaski, G Pacileo… - Heart Failure …, 2018 - heartfailure.theclinics.com
Cardiomyopathies (CMPs) are myocardial disorders in which the heart muscle is structurally
and functionally abnormal in the absence of abnormal conditions that can explain the …

Molecular basis of familial cardiomyopathies

K Schwartz, L Carrier, P Guicheney, M Komajda - Circulation, 1995 - Am Heart Assoc
Cardiomyopathies represent a variety of cardiac diseases that are an important cause of
morbidity and mortality throughout the world in children and adults and whose definition and …

[HTML][HTML] Genetics of Dilated Cardiomyopathy

R Eldemire, L Mestroni… - Annual review of medicine, 2024 - annualreviews.org
Dilated cardiomyopathy (DCM) is defined as dilation and/or reduced function of one or both
ventricles and remains a common disease worldwide. An estimated 40% of cases of familial …

Genetics of inherited cardiomyopathy

D Jacoby, WJ McKenna - European heart journal, 2012 - academic.oup.com
During the past two decades, numerous disease-causing genes for different
cardiomyopathies have been identified. These discoveries have led to better understanding …

Genetics of sudden cardiac death caused by ventricular arrhythmias

RF Marsman, HL Tan, CR Bezzina - Nature reviews Cardiology, 2014 - nature.com
Sudden cardiac death (SCD) resulting from ventricular tachyarrhythmia is a major
contributor to mortality. Clinical management of SCD, currently based on clinical markers of …

Diagnosis, prevalence, and screening of familial dilated cardiomyopathy

ME Sweet, MRG Taylor, L Mestroni - Expert opinion on orphan …, 2015 - Taylor & Francis
Introduction: Dilated cardiomyopathy (DCM) is the most common cardiomyopathy and
occurs often in families. As an inherited disease, understanding the significance of …

Molecular mechanisms of arrhythmogenic cardiomyopathy

KM Austin, MA Trembley, SF Chandler… - Nature Reviews …, 2019 - nature.com
Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …