Fluoroquinolones are broad-spectrum antimicrobials highly effective in the treatment of a
wide variety of clinical infections. Salmonella gastroenteritis is usually only treated with …

Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a rapid
screening and identification method for DNA sequence variation detection in the quinolone …

We developed a novel rapid assay to detect the gyrA mutations that cause quinolone
resistance in typhoid and paratyphoid fever Salmonella spp. using high-resolution melting …

ABSTRACT Salmonella enterica isolates (n= 182) were examined for mutations in the
quinolone resistance-determining region of gyrA, gyrB, parC, and parE. The frequency …

A total of 63 isolates were screened for the gyrA mutation (87Asp–Tyr) in Salmonella
enterica serovars using real time PCR. All of the isolates were successfully identified as …

The quinolone resistance-determining regions (QRDRs) of the gyrA genes of quinolone-
resistant clinical and veterinary salmonella isolates were sequenced. Substitutions …

Objectives Decreased susceptibility to fluoroquinolones has become a major problem for the
successful therapy of human infections caused by Salmonella enterica, especially the life …

In recent decades, the emergence and spread of resistance to nalidixic acid are usually
associated with reduced susceptibility to ciprofloxacin among Salmonella serotypes. The …

Aims: Quinolone antibiotics are the agents of choice for treating systemic Salmonella
infections. Resistance to quinolones is usually mediated by mutations in the DNA gyrase …

Resistance to quinolone antibiotics has been associated with single-nucleotide
polymorphisms (SNPs) in the quinolone resistance-determining region (QRDR) of gyrA …