Abstract Walsh, FM, and Sode, Jonas: Significance of non-steady-state serum digoxin
concentrations. Am J Clin Pathol 63: 446–450, 1975. In order better to define the optimal …

A radioimmunoassay for serum digoxin concentration has been used to study the
interrelationships of circulating levels of the drug and various factors in the clinical setting in …

Plasma digoxin levels were determined in 6 healthy, young male subjects by
radioimmunoassay. All were given an oral dose of 1.0 mg. of digoxin the first day, followed …

Methods During the period of July, 1971, to June, 1973, the serum digoxin concentration
was determined in Over 1,200 patients admitted to the University of Kansas Medical Center …

Using the radioimmunoassay technique for measuring serum digoxin, it was found that
patients who were given 0.25 mg. digoxin orally per day had a mean serum level of …

A retrospective study of 1,269 patients on digoxin was done to determine the relationship
between serum digoxin levels of 3.0 ng/ml or higher and clinical toxicity. Of 1,269 patients …

Serum and myocardial digoxin levels were studied in 18 patients who came to autopsy. An
independent analysis of electrocardiograms prior to death was made to ascertain the …

No significant differences were found between plasma digoxin concentrations in samples
assayed by both radioimmunoassay and 86 Rb uptake. The mean plasma digoxin …

Forty-seven patients who were being treated with digoxin in a daily dose range of 0.25 mg.
to 0.75 mg. were the study material. Thirty-two patients were toxic. Seven patients out of …

The unexplained association of unusually large maintenance doses of digoxin and low
serum digoxin concentrations in several patients prompted a study of the biologic availability …