Staphylococcal and streptococcal superantigens are exotoxins that may be linked to many
human pathologies involving impaired immune functions. Despite considerable sequence …

Superantigens exert their pathologic effects by direct binding to major histocompatibility
complex (MHC) class II molecules and T cell antigen receptors (TCR), thus circumventing …

The exotoxins produced by Staphylococcus aureus, staphylococcal enterotoxins (SE) AE
and toxic shock syndrome toxin (TSST)-1, which are associated with serious diseases …

Staphylococcal exotoxins, staphylococcal enterotoxins AE (SEA-SEE), and toxic shock
syndrome toxin-1 (TSST-1) are potent activators of the immune system and cause a variety …

Staphylococcus aureus and Streptococcus pyogenes secrete exotoxins that act as
superantigens, proteins that cause hyperimmune reactions by binding the variable domain …

The pyrogenic exotoxins of group A streptococci (SPEs) and the enterotoxins of
Staphylococcus aureus (SEs) constitute a family of structurally related toxins that also share …

Superantigens produced by Staphylococcus aureus and Streptococcus pyogenes are
among the most lethal of toxins. Toxins in this large family trigger an excessive cellular …

The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …

Exotoxins of Staphylococcus aureus belong to a family of bacterial proteins that act as
superantigens by activating a large subset of the T-cell population, causing massive release …

Bacterial superantigens (BSAgs) cause massive stimulation of the immune system and are
associated with various pathologies and diseases. To address the role of antibodies in …