We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

The translocation t (8; 21)(q22; q22) occurs in 6 to 12 percent of patients with AML, and
usually predicts a good response to chemotherapy with a high remission rate and a …

Chromosome 21 and in particular band 21q22, the site of AML1 (RUNX1, CBFA2) gene, is
among the most frequent targets of chromosomal translocations in leukemia observed in …

Abstract A translocation (6; 11)(q26–27; q23) was detected in four male patients diagnosed
with acute T-cell lymphoblastic leukemia and acute myelomonocytic and monocytic …

Objective To investigate the clinical and laboratory features of acute myeloid leukemia
(AML) with t (11; 12)(p15; q13) translocation. Methods Two cases of AML with t (11; 12)(p15; …

Studies of large numbers of patients have enabled the identification of relatively infrequent
chromosome changes, such as inv (3)(q21; q26), t (6; 9)(p23; q34) and t (8; 16)(p11; p11) …

We report a case of acute myelogenous leukemia with a variant translocation involving
chromosomes 5 and 21 with breakpoints on 5813 and 21822 as revealed by various …

The translocation t (8; 21)(q22; q22) is found in 40% of cases of acute myeloid leukemia
(AML) designated as the subtype M2 in the French-American-British (FAB) classification …

Abstract The t (8; 21)(q22; q22) with the resulting RUNX1-RUNX1T1 rearrangement is one
of the most common cytogenetic abnormalities in acute myeloid leukemia (AML). It is …

Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …