Protocol 15PRT/06897: objective randomised blinded investigation with optimal medical therapy of angioplasty in stable angina (ORBITA trial)‐NCT02062593 …

DP Francis, JE Davies, R Al-Lamee, S Thom… - Lancet, 2016 - thelancet.com
Background Percutaneous coronary intervention (PCI) is commonly used to relieve
symptoms in chronic stable angina. However, there has no been no study of PCI against a …

Rethinking revascularization in patients with stable angina

RE Harskamp, DW Park - Expert Review of Cardiovascular …, 2018 - Taylor & Francis
Introduction: Traditional and current perception for benefit of percutaneous coronary
intervention (PCI) is that patients with stable angina will obtain symptom relief as well as …

[HTML][HTML] A double-blind randomised placebo-controlled trial of percutaneous coronary intervention for the relief of stable angina without antianginal medications …

AN Nowbar, C Rajkumar, M Foley… - …, 2022 - ncbi.nlm.nih.gov
Percutaneous coronary intervention (PCI) is frequently performed for stable angina.
However, the first blinded trial, ORBITA, did not show a placebo-controlled increment in …

Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial

R Al-Lamee, D Thompson, HM Dehbi, S Sen, K Tang… - The Lancet, 2018 - thelancet.com
Background Symptomatic relief is the primary goal of percutaneous coronary intervention
(PCI) in stable angina and is commonly observed clinically. However, there is no evidence …

[HTML][HTML] Quality of life assessment in trials of revascularization for chronic stable angina: insights from ORBITA and the implications of blinding

AN Nowbar, DP Francis, RK Al-Lamee - Cardiovascular drugs and therapy, 2022 - Springer
The main aims of therapy in chronic stable angina are to reduce the risk of myocardial
infarction and death and improve symptoms and quality of life (QoL). Unblinded trials have …

PCI for stable angina

GB Lim - Nature Reviews Cardiology, 2024 - nature.com
PCI for stable angina | Nature Reviews Cardiology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

[PDF][PDF] Revisiting the role of percutaneous coronary interventions in stable angina: The landscape after the COURAGE trial

M Koziński, A Sukiennik - Cardiology Journal, 2007 - journals.viamedica.pl
The release of the COURAGE trial results has fuelled the debate over the benefits of
percutaneous coronary interventions (PCI) in stable angina [1]. To date PCI, when compared …

[HTML][HTML] A placebo-controlled trial of percutaneous coronary intervention for stable angina

CA Rajkumar, MJ Foley, F Ahmed-Jushuf… - … England Journal of …, 2023 - Mass Medical Soc
Background Percutaneous coronary intervention (PCI) is frequently performed to reduce the
symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in …

Subjective angina or myocardial ischaemia to justify PCI? Never mistake the finger for the moon

A Spirito, D Cao, R Mehran - European Heart Journal, 2022 - academic.oup.com
In recent years, new evidence redefined the role of coronary revascularization in the
management of patients with chronic coronary syndrome (CCS). The primacy of coronary …

The argument of the ORBITA study: angioplasty is useless

L Bolognese - European Heart Journal Supplements, 2020 - academic.oup.com
The goal of treatment in stable coronary artery disease is to improve prognosis and quality of
life of the patients. International Guidelines support revascularization procedures for …