Adherence to drug-refill is a useful early warning indicator of virologic and immunologic failure among HIV patients on first-line ART in South Africa

Z El-Khatib, D Katzenstein, G Marrone, F Laher… - PloS one, 2011 - journals.plos.org
Background Affordable strategies to prevent treatment failure on first-line regimens among
HIV patients are essential for the long-term success of antiretroviral therapy (ART) in sub …

Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon

M Rougemont, BE Stoll, N Elia, P Ngang - AIDS research and therapy, 2009 - Springer
Abstract Background With African health-care systems facing exploding demand for HIV
care, reliable methods for assessing adherence and its influencing factors are needed to …

Simple adherence assessments to predict virologic failure among HIV-infected adults with discordant immunologic and clinical responses to antiretroviral therapy

JD Goldman, RA Cantrell, LB Mulenga… - AIDS research and …, 2008 - liebertpub.com
We evaluated the association between two antiretroviral therapy (ART) adherence
measurements—the medication possession ratio (MPR) and patient self-report—and …

Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study

S Nsanzimana, M Semakula, V Ndahindwa… - BMC infectious …, 2019 - Springer
Background Currently, there is limited evidence on the effectiveness of second-line
antiretroviral therapy (ART) in sub-Saharan Africa. To address this challenge, outcomes of …

Patient retention and adherence to antiretrovirals in a large antiretroviral therapy program in Nigeria: a longitudinal analysis for risk factors

M Charurat, M Oyegunle, R Benjamin, A Habib, E Eze… - PloS one, 2010 - journals.plos.org
Background Substantial resources and patient commitment are required to successfully
scale-up antiretroviral therapy (ART) and provide appropriate HIV management in resource …

High levels of adherence and viral suppression in a nationally representative sample of HIV-infected adults on antiretroviral therapy for 6, 12 and 18 months in …

B Elul, P Basinga, H Nuwagaba-Biribonwoha, S Saito… - PloS one, 2013 - journals.plos.org
Background Generalizable data are needed on the magnitude and determinants of
adherence and virological suppression among patients on antiretroviral therapy (ART) in …

Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes?

C Orrell, K Cohen, R Leisegang, DR Bangsberg… - AIDS Research and …, 2017 - Springer
Background Incomplete adherence to antiretroviral therapy (ART) results in virologic failure
and resistance. It remains unclear which adherence measure best predicts these outcomes …

The combination of pill count and self-reported adherence is a strong predictor of first-line ART failure for adults in South Africa

P Wu, BA Johnson, JB Nachega, B Wu… - Current HIV …, 2014 - ingentaconnect.com
Background: Suboptimal adherence to antiretroviral therapy (ART) is a strong predictor of
virologic failure (VF) among people with HIV. Various methods such as patient self-report …

Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy

GP Bisson, R Gross, S Bellamy, J Chittams… - PLoS …, 2008 - journals.plos.org
Background World Health Organization (WHO) guidelines for monitoring HIV-infected
individuals taking combination antiretroviral therapy (cART) in resource-limited settings …

Comparison of pharmacy-based measures of adherence to antiretroviral therapy as predictors of virological failure

CE Henegar, D Westreich, M Maskew, MA Brookhart… - AIDS and Behavior, 2015 - Springer
We compared multiple pharmacy refill-based adherence indicators for antiretroviral therapy,
as well as thresholds for defining non-adherent behavior, based on ability to predict …