The chymase-angiotensin system in humans
A Husain - Journal of hypertension, 1993 - journals.lww.com
Angiotensin II (Ang II) has diverse effects on the car-diovascular system, including
vasoconstriction and aldosterone secretion, and produces positive inotropic and …
vasoconstriction and aldosterone secretion, and produces positive inotropic and …
Chymase-dependent angiotensin II forming system in humans
H Urata, H Nishimura, D Ganten - American journal of hypertension, 1996 - Elsevier
Recent studies have provided evidence that human cardiovascular tissues contain
components of the renin angiotensin system: angiotensinogen, renin, angiotensin I …
components of the renin angiotensin system: angiotensinogen, renin, angiotensin I …
The chymase-angiotensin system in humans: biochemistry, molecular biology and potential role in cardiovascular diseases.
Y Liao, A Husain - The Canadian Journal of Cardiology, 1995 - europepmc.org
Angiotensin I-converting enzyme (ACE) inhibitors are highly effective in the treatment of
cardiovascular diseases. However, the relationship among the antihypertensive effects of …
cardiovascular diseases. However, the relationship among the antihypertensive effects of …
Chymase-dependent angiotensin II formation in human vascular tissue
S Takai, D Jin, M Sakaguchi, M Miyazaki - Circulation, 1999 - Am Heart Assoc
Background—Some reports have suggested that, in vitro, human heart chymase in
homogenates contributes little to angiotensin (Ang) II formation in the presence of natural …
homogenates contributes little to angiotensin (Ang) II formation in the presence of natural …
Angiotensin I converting enzyme and chymase in cardiovascular tissues.
H Nishimura, S Hoffmann, O Baltatu… - Kidney International …, 1996 - search.ebscohost.com
Recent studies have provided evidence that the human cardiovascular tissues contain
components of the renin-angiotensin system; angiotensinogen, renin, angiotensin I …
components of the renin-angiotensin system; angiotensinogen, renin, angiotensin I …
Local angiotensin II-generating system in vascular tissues: the roles of chymase
M Miyazaki, S Takai - Hypertension Research, 2001 - jstage.jst.go.jp
Roles of each angiotensin II producing enzymes of each of the angiotensin Il-producing
enzymes were reviewed based on experimental models. In vascular tissues, angiotensin II is …
enzymes were reviewed based on experimental models. In vascular tissues, angiotensin II is …
Mechanisms of angiotensin H formation in humans
H Urata, H Nishimura, D Ganten - European heart journal, 1995 - academic.oup.com
Various organs, including the heart and blood vessels, apparently contain tissue renin-
angiotensin systems. Through autocrine and paracrine activity, locally produced angiotensin …
angiotensin systems. Through autocrine and paracrine activity, locally produced angiotensin …
Implications of species difference for clinical investigation: studies on the renin-angiotensin system
NK Hollenberg - Hypertension, 2000 - Am Heart Assoc
The justification for clinical investigation has its roots in the fact that physiological
mechanisms and disease pathogenesis in animal models replicate mechanisms and …
mechanisms and disease pathogenesis in animal models replicate mechanisms and …
Widespread tissue distribution of human chymase.
H Urata, F Strobel, D Ganten - … Journal of the International Society of …, 1994 - europepmc.org
Objective Human chymase is a potent and specific angiotensin (Ang) II-forming serine
proteinase. Although the histological localization of heart chymase indicated that this …
proteinase. Although the histological localization of heart chymase indicated that this …
The angiotensin converting enzyme in the kidney
F Alhenc-Gelas, T Baussant, C Hubert… - Journal of …, 1989 - journals.lww.com
Immunohistochemical studies and experiments with microdissected nephron segments
indicate that the angiotensin I converting enzyme (ACE) in the kidney is expressed in the …
indicate that the angiotensin I converting enzyme (ACE) in the kidney is expressed in the …