Cbx2 as a Therapeutic Target in Colorectal Cancer: Insights into the Altered Chromatin Accessibility Via Runx1-Cbx2-Map4k1 Axis

B Wang, S Zhang, C Tang, Y Guo, W Gao, H Wu… - Available at SSRN … - papers.ssrn.com
Abstract Chromobox homolog 2 (CBX2), a component of the polycomb repressive complex
1, is overexpressed in various cancers, but its specific role in colorectal cancer (CRC) is not …
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[HTML] nih.gov

[HTML][HTML] Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer

J Tang, G Wang, M Zhang, F Li, Y Sang, B Wang… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The effect of polycomb chromobox (Cbx) proteins in cancer is context-dependent. The
Chromobox homolog 8 (CBX8) was originally characterized as a transcriptional repressor …
被引用次数：60 相关文章 所有 8 个版本
[PDF] springer.com

m6A modification-mediated CBX8 induction regulates stemness and chemosensitivity of colon cancer via upregulation of LGR5

Y Zhang, M Kang, B Zhang, F Meng, J Song, H Kaneko… - Molecular cancer, 2019 - Springer
Background Colon cancer (CC) cells can exhibit stemness and expansion capabilities,
which contribute to resistance to conventional chemotherapies. Aberrant expression of …
被引用次数：114 相关文章 所有 11 个版本
[PDF] frontiersin.org

Comprehensive analysis of prognostic value and immune infiltration of chromobox family members in colorectal cancer

Q Li, Y Pan, Z Cao, S Zhao - Frontiers in oncology, 2020 - frontiersin.org
Objective: Colorectal cancer (CRC) is one of the common malignant tumors worldwide.
Chromobox (CBX) family proteins are important components of epigenetic regulation …
被引用次数：59 相关文章 所有 7 个版本
[PDF] springer.com

Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses

H Zhou, Y Xiong, Z Liu, S Hou, T Zhou - Cancer cell international, 2021 - Springer
Abstract Background The Chromobox (CBX) domain protein family, a core component of
polycomb repressive complexes 1, is involved in transcriptional repression, cell …
被引用次数：24 相关文章 所有 11 个版本

CBX4 suppresses metastasis via recruitment of HDAC3 to the Runx2 promoter in colorectal carcinoma

X Wang, L Li, Y Wu, R Zhang, M Zhang, D Liao… - Cancer research, 2016 - AACR
Polycomb chromobox (CBX) proteins participate in the polycomb repressive complex
(PRC1) that mediates epigenetic gene silencing and endows PRC1 with distinct oncogenic …
被引用次数：76 相关文章 所有 4 个版本
[HTML] nih.gov

[HTML][HTML] CBX2 Deletion Suppresses Growth and Metastasis of Colorectal Cancer by Mettl3-p38/ERK MAPK Signalling Pathway

R Sun, X Tu, S Chan, X Wang, Y Ji, Z Wang… - Journal of …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) seriously endangers human health owing to its high morbidity and
mortality. Previous studies have suggested that high expression of CBX2 may be associated …
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[PDF] archive.org

[PDF][PDF] Expression and prognostic significance of CBX2 in colorectal cancer: Database mining for CBX family members in malignancies

H Zhou, Y Xiong, Z Liu, S Hou, T Zhou - 2021 - scholar.archive.org
Abstract Background: The Chromobox (CBX) domain protein family, a core component of
polycomb repressive complexes 1, is involved in transcriptional repression, cell …
相关文章 所有 3 个版本
[PDF] frontiersin.org

CBX7 is dualistic in cancer progression based on its function and molecular interactions

J Li, T Ouyang, M Li, T Hong, MHS Alriashy… - Frontiers in …, 2021 - frontiersin.org
Chromobox protein homolog 7 (CBX7) is a member of the Chromobox protein family and
participates in the formation of the polycomb repressive complex 1 (PRC1). In cells, CBX7 …
被引用次数：15 相关文章 所有 5 个版本
[PDF] springer.com

CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway

N Del Gaudio, A Di Costanzo, NQ Liu, L Conte… - Molecular cancer, 2022 - Springer
Background The dynamic epigenome and proteins specialized in the interpretation of
epigenetic marks critically contribute to leukemic pathogenesis but also offer alternative …
被引用次数：23 相关文章 所有 14 个版本