Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase
GC Brown - FEBS letters, 1995 - Wiley Online Library
Nitric oxide (NO) reversibly inhibits mitochondrial respiration by competing with oxygen at
cytochrome oxidase. Concentrations of NO measured in a range of biological systems are …
cytochrome oxidase. Concentrations of NO measured in a range of biological systems are …
[HTML][HTML] Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
GC Brown - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2001 - Elsevier
Nitric oxide (NO) and its derivatives inhibit mitochondrial respiration by a variety of means.
Nanomolar concentrations of NO immediately, specifically and reversibly inhibit cytochrome …
Nanomolar concentrations of NO immediately, specifically and reversibly inhibit cytochrome …
[HTML][HTML] Nitric oxide and mitochondrial respiration
GC Brown - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1999 - Elsevier
Nitric oxide (NO) and its derivative peroxynitrite (ONOO−) inhibit mitochondrial respiration by
distinct mechanisms. Low (nanomolar) concentrations of NO specifically inhibit cytochrome …
distinct mechanisms. Low (nanomolar) concentrations of NO specifically inhibit cytochrome …
Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain
GC Brown - Acta physiologica scandinavica, 2000 - Wiley Online Library
Nitric oxide (NO) and its derivatives inhibit mitochondrial respiration by various means. The
author and others have shown that low (nanomolar) concentrations of NO immediately …
author and others have shown that low (nanomolar) concentrations of NO immediately …
Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide
V BORUTAITÉ, GC Brown - Biochemical Journal, 1996 - portlandpress.com
Nitric oxide (NO) inhibited the respiration rate of mitochondria isolated from rat heart at sub-
micromolar concentrations of NO. The inhibition was rapidly and completely reversible …
micromolar concentrations of NO. The inhibition was rapidly and completely reversible …
Nitric oxide inhibition of cytochrome oxidase and mitochondrial respiration: implications for inflammatory, neurodegenerative and ischaemic pathologies
GC Brown - Detection of Mitochondrial Diseases, 1997 - Springer
Nitric oxide (NO) at high levels is cytotoxic, and may be involved in a range of inflammatory,
neurodegenerative, and cardio-vascular/ischaemic pathologies. The mechanism of NO …
neurodegenerative, and cardio-vascular/ischaemic pathologies. The mechanism of NO …
Oxygen-dependent regulation of mitochondrial energy metabolism by nitric oxide
Y Takehara, T Kanno, T Yoshioka, M Inoue… - Archives of Biochemistry …, 1995 - Elsevier
To elucidate the role of nitric oxide (NO) in the regulation of mitochondrial function, the effect
of NO on energy transfer reactions was examined under different oxygen tensions …
of NO on energy transfer reactions was examined under different oxygen tensions …
Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism
C GIULIVI - Biochemical Journal, 1998 - portlandpress.com
The effects of endogenous production of NO•, catalysed by the mitochondrial nitric oxide
synthase (NOS), on mitochondrial metabolism were studied. The respiratory rates of intact …
synthase (NOS), on mitochondrial metabolism were studied. The respiratory rates of intact …
The effect of nitric oxide on mitochondrial respiration
JJ Poderoso, K Helfenberger, C Poderoso - Nitric oxide, 2019 - Elsevier
This article reviews the interactions between nitric oxide (NO) and mitochondrial respiration.
Mitochondrial ATP synthesis is responsible for virtually all energy production in mammals …
Mitochondrial ATP synthesis is responsible for virtually all energy production in mammals …
Nitric oxide, cytochrome c and mitochondria
GC Brown, V Borutaite - Biochemical Society Symposia, 1999 - portlandpress.com
Nitric oxide (NO) and its derivative, peroxynitrite (ONOO-), inhibit mitochondrial respiration,
and this inhibition may contribute to both the physiological and cytotoxic actions of NO …
and this inhibition may contribute to both the physiological and cytotoxic actions of NO …
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