Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
Spirometric measures of lung function are heritable traits that reflect respiratory health and
predict morbidity and mortality. We meta-analyzed genome-wide association studies for two …
predict morbidity and mortality. We meta-analyzed genome-wide association studies for two …
Genome-wide association study identifies five loci associated with lung function
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung
volume and is used to diagnose and monitor lung diseases. We performed genome-wide …
volume and is used to diagnose and monitor lung diseases. We performed genome-wide …
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function
Genome-wide association studies have identified numerous genetic loci for spirometic
measures of pulmonary function, forced expiratory volume in one second (FEV1), and its …
measures of pulmonary function, forced expiratory volume in one second (FEV1), and its …
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation
Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease.
In 38,199 European ancestry individuals, we studied genome-wide association of forced …
In 38,199 European ancestry individuals, we studied genome-wide association of forced …
A genome-wide association study of pulmonary function measures in the Framingham Heart Study
The ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC) is a
measure used to diagnose airflow obstruction and is highly heritable. We performed a …
measure used to diagnose airflow obstruction and is highly heritable. We performed a …
Framingham Heart Study genome-wide association: results for pulmonary function measures
Background Pulmonary function measures obtained by spirometry are used to diagnose
chronic obstructive pulmonary disease (COPD) and are highly heritable. We conducted …
chronic obstructive pulmonary disease (COPD) and are highly heritable. We conducted …
A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity
Background Lung function is a heritable complex phenotype with obesity being one of its
important risk factors. However, knowledge of their shared genetic basis is limited. Most …
important risk factors. However, knowledge of their shared genetic basis is limited. Most …
[HTML][HTML] Molecular mechanisms underlying variations in lung function: a systems genetics analysis
Background Lung function measures reflect the physiological state of the lung, and are
essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta …
essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta …