Early detection by newborn screening and appropriate L-thyroxine treatment leads to normal
or near-normal neurocognitive outcome in infants with congenital hypothyroidism. Many …

OBJECTIVES: To compare neurodevelopmental outcomes in severe and moderate
congenital hypothyroidism (CH) among 3 different initial L-thyroxine doses and to examine …

Unrecognized congenital hypothyroidism leads to mental retardation. Newborn screening
and thyroid therapy started within 2 weeks of age can normalize cognitive development. The …

Background: Congenital hypothyroidism (CH) is the most frequent congenital endocrine
disorder. The diagnosis in industrialized countries is usually made with population-based …

The appropriateness of the recommended L-thyroxine dose (10-15 μg/kg/day) for the
treatment of congenital hypothyroidism has been questioned because of the risk of …

Systematic neonatal screening for congenital hypothyroidism (CH), which was progressively
implemented in industrialized countries over the past 15 to 25 years, has been extremely …

Neonatal screening programs for congenital hypothyroidism (CH) were initiated in the 1970s
to ensure early treatment in order to prevent mental retardation. With screening …

Objective. To compare the effects of therapy with thyroxine (T4) plus triiodothyronine (T3)
versus T4 alone from the first days of life in screened congenital hypothyroid (CH) infants …

The increased survival of very low birth weight (VLBW) premature infants has been
associated with an increased prevalence of transient disorders of thyroid function during the …

Abstract Congenital hypothyroidism, occurring in 1: 3000 newborns, is one of the most
common preventable causes of mental retardation. Neurodevelopmental outcome is …