Thyroid hormone levels have a crucial role for optimal brain development from gestation
through the first 2 postnatal years. However, thyroid hormones vary with gestational age …

The aim of this study was to determine the neuropsychologic development in patients with
congenital (primary) hypothyroidism (CH) detected by screening and treated from early age …

Background Premature infants who have transient hypothyroxinemia in the first weeks of life
may have developmental delay and neurologic dysfunction. Whether thyroxine treatment …

Objective. To describe intellectual, motor, and school-associated outcome in young adults
with early treated congenital hypothyroidism (CH) and to study the association between long …

Although neonatal thyroid screening programs have been of value in preventing cerebral
damage, it is still controversial whether patients with congenital hypothyroidism achieve …

Background Transient hypothyroxinemia, a common finding in premature infants, is not
thought to have long-term sequelae or to require treatment. We investigated whether …

4 in VLBW infants (< 30 weeks or< 1200-1500 g) decline progressively after day 1, reaching
a nadir at 1 to 2 weeks of age. This relative hypothyroxinemia is most profound in those …

Background: Despite newborn screening and early levothyroxine replacement, there are
continued reports of mild neurocognitive impairment in children with congenital …

Objective To determine the evolution of congenital hypothyroidism in preterms and the
clinical features of permanent forms. Study design We retrospectively evaluated 24 preterm …

Context: Long-term follow-up data on cognitive and motor functioning in adult patients with
congenital hypothyroidism, diagnosed by neonatal screening, are scarce. Hence, it is still …