Identification of immune-related hub genes in Parkinson's disease

L Chen, Y Wang, J Huang, B Hu, W Huang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a common, age-related, and progressive
neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an …

Novel diagnostic biomarkers related to immune infiltration in Parkinson's disease by bioinformatics analysis

P Zhang, L Zhao, H Li, J Shen, H Li… - Frontiers in Neuroscience, 2023 - frontiersin.org
Background Parkinson's disease (PD) is Pengfei Zhang Liwen Zhao Pengfei Zhang Liwen
Zhao a common neurological disorder involving a complex relationship with immune …

Identifying the hub gene and immune infiltration of Parkinson's disease using bioinformatical methods

SH Liu, YL Wang, SM Jiang, XJ Wan, JH Yan, CF Liu - Brain Research, 2022 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disorder that affects
1%–2% of the population over 60 years old. Immune response dysfunction in the brain …

Identification of potential immune-related hub genes in Parkinson's disease based on machine learning and development and validation of a diagnostic classification …

G Xin, J Niu, Q Tian, Y Fu, L Chen, T Yi, K Tian, X Sun… - PloS One, 2023 - journals.plos.org
Background Parkinson's disease is the second most common neurodegenerative disease in
the world. However, current diagnostic methods are still limited, and available treatments …

Immune profiling of Parkinson's disease revealed its association with a subset of infiltrating cells and signature genes

X Zhang, Z Shao, S Xu, Q Liu, C Liu, Y Luo… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is an age-related and second most common neurodegenerative
disorder. In recent years, increasing evidence revealed that peripheral immune cells might …

[HTML][HTML] Integrative analysis of potential biomarkers and immune cell infiltration in Parkinson's disease

X Chen, W Cao, Y Zhuang, S Chen, X Li - Brain Research Bulletin, 2021 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disease in the
elderly population. However, there are no reliable diagnostic biomarkers for PD, and the …

Significant difference of immune cell fractions and their correlations with differential expression genes in Parkinson's disease

Y Huang, H Liu, J Hu, C Han, Z Zhong… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most neurodegenerative disease in the world. T cell
infiltration in the central nervous system (CNS) has provided insights that the peripheral …

Identification of immune hub genes associated with braak stages in Alzheimer's Disease and their correlation of immune infiltration

X Qian, X Liu, S Chen, H Tang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Background Alzheimer's disease (AD) is the most common type of neurodegenerative
disease. Tau pathology is one of the pathological features of AD, and its progression is …

Network and pathway-based analyses of genes associated with Parkinson's disease

Y Hu, Z Pan, Y Hu, L Zhang, J Wang - Molecular neurobiology, 2017 - Springer
Parkinson's disease (PD) is a major neurodegenerative disease influenced by both genetic
and environmental factors. Although previous studies have provided insights into the …

Genome-wide pathway-based association analysis identifies risk pathways associated with Parkinson's disease

M Zhang, H Mu, Z Shang, K Kang, H Lv, L Duan, J Li… - Neuroscience, 2017 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease. It is
generally believed that it is influenced by both genetic and environmental factors, but the …